Huang H J, Yamazaki H, Kawabata H, Ninomiya T, Adachi-Usami E
Department of Ophthalmology, Kohnodai Hospital, National Center of Neurology and Psychiatry, Chiba, Japan.
Doc Ophthalmol. 1996;92(4):301-9. doi: 10.1007/BF02584084.
Electrophysiologic findings including multifocal electroretinogram and visual evoked cortical potentials were studied in a patient with multiple evanescent white dot syndrome. A 19-year-old woman was diagnosed as having multiple evanescent white dot syndrome because of decreased visual acuity, white dots on fundus examination and hyperfluorescence of the white dots in the right eye. The amplitude of the flicker electroretinogram was reduced, but the single-flash electroretinogram was within the normal range. The P100 latency of the pattern visual evoked cortical potentials was slightly prolonged. The amplitudes of multifocal electroretinogram were markedly reduced in the area corresponding to the scotoma and moderately reduced in other regions of the central field in the affected eye. The results suggest that the retinal dysfunction area is wider than that detected by subjective methods or conventional electrophysiological examinations. The delayed recovery of the visual evoked cortical potential latency suggests the involvement of the optic nerve in multiple evanescent white dot syndrome.
对一名多发性一过性白点综合征患者进行了包括多焦视网膜电图和视觉诱发电位皮质电位在内的电生理检查。一名19岁女性因视力下降、眼底检查发现白点以及右眼白点处高荧光而被诊断为多发性一过性白点综合征。闪光视网膜电图的振幅降低，但单次闪光视网膜电图在正常范围内。图形视觉诱发电位皮质电位的P100潜伏期略有延长。患眼多焦视网膜电图的振幅在与暗点对应的区域明显降低，在中心视野的其他区域中度降低。结果表明，视网膜功能障碍区域比主观方法或传统电生理检查所检测到的区域更广泛。视觉诱发电位皮质电位潜伏期恢复延迟提示视神经受累于多发性一过性白点综合征。
