Fejgin M D, Cohen I, Horvat-Kohlmann M, Charles A G, Luzon A, Samra Z
Department of Obstetrics and Gynecology, Michael Reese Medical Center, Chicago, Illinois, USA.
Isr J Med Sci. 1997 Feb;33(2):98-102.
In an attempt to prove the presence of intrauterine fetal chlamydial infection, sera from 26 laboring women, who tested positive for cervical chlamydial antigen in the first half of their pregnancies, and from 43 laboring women with no evidence of such infection, and sera from the cord of their delivered infants were tested for chlamydial IgA-, IgG- and IgM-specific antibodies. Nine (34.6%) of the 26 women with positive cervical infection and 5 (11.6%) of the 43 women with no identifiable cervical infection had significant antibody levels at the time of the delivery. Three of the 26 (11.5%) babies born to the mothers with positive cervical chlamydial infection early in the pregnancy and high antibody titer at delivery were found to have anti-chlamydial antibodies in their cord serum, indicating intrauterine infection; cord sera from the other 43 babies were negative for these antibodies. These findings suggest a low but possible risk of intrauterine infection in the presence of lower genital infection during pregnancy.
为了证实宫内胎儿衣原体感染的存在，对26名在妊娠前半期宫颈衣原体抗原检测呈阳性的临产妇女、43名无此类感染证据的临产妇女以及她们所分娩婴儿的脐带血血清进行了衣原体IgA、IgG和IgM特异性抗体检测。26名宫颈感染阳性的妇女中有9名（34.6%），43名未发现宫颈感染的妇女中有5名（11.6%）在分娩时抗体水平显著。26名妊娠早期宫颈衣原体感染阳性且分娩时抗体滴度高的母亲所生的婴儿中有3名（11.5%）脐带血清中发现有抗衣原体抗体，表明存在宫内感染；其他43名婴儿的脐带血清中这些抗体呈阴性。这些发现表明，孕期下生殖道感染时存在宫内感染的风险较低但有可能。
