Shahar E, Lorber M
Institute of Clinical Immunology, Allergy and AIDS, Rambam Medical Center, Haifa, Israel.
Isr J Med Sci. 1997 Feb;33(2):147-9.
Autoimmune conditions and allergic diseases are both characterized by immune dysregulation. The purpose of this study was to evaluate the incidence of various allergic disorders in patients with systemic lupus erythematosus (SLE). Sixty patients with SLE completed a questionnaire detailing their allergic disorders, which we compared with those of 60 age- and sex-matched healthy people. Forty-four of the SLE patients (56%) had at least one type of allergic disorder. Perturbation of immunoregulation in SLE patients may increase the susceptibility to develop IgE-mediated allergic disorders.
自身免疫性疾病和过敏性疾病都具有免疫失调的特征。本研究的目的是评估系统性红斑狼疮（SLE）患者中各种过敏性疾病的发病率。60例SLE患者完成了一份详细描述其过敏性疾病的问卷，我们将其与60名年龄和性别匹配的健康人进行了比较。44例SLE患者（56%）至少有一种过敏性疾病。SLE患者免疫调节的紊乱可能会增加发生IgE介导的过敏性疾病的易感性。
