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National Cancer Institute, Frederick Cancer Research and Development Center, MD 21702-1201, USA.
Trends Biochem Sci. 1997 Jul;22(7):273-4. doi: 10.1016/s0968-0004(97)01080-3.
Methods and reagents is a unique monthly column that highlights current discussion in the newsgroup bionet.molibio.methds-reagnts, available on the internet. This month's column discusses the pros and cons of various techniques used to shear DNA for shotgun cloning. For details on how to partake in the newsgroup, see the accompanying box.