Naranjo J A, Mañas M, Valverde A, Yago M D, Martínez-Victoria E
Instituto de Nutrición y Tecnología de Alimentos, Departamento de Fisiología, University of Granada, Spain.
Arch Physiol Biochem. 1997 Apr;105(2):190-6. doi: 10.1076/apab.105.2.190.12923.
Suckling goats were fed ad libitum during the first month of their life by goat milk or by a milk replacer. These diets differed in the amount of fat and the type of protein. The composition of the exocrine pancreatic secretion in the basal period and in response to food were compared in both conditions. Pancreatic juice was collected one hour before meal intake up to the 8th postprandial hour. Pancreatic flow rate, bicarbonate and chloride levels, total protein and enzyme activities were measured. In resting conditions and in response to food, the lipase activity was found to be significantly lower in the group fed with milk replacer, which was poorer in fat. These results indicate an adaptation of the enzyme output to the available quantity of its substrate, similar to that described in the rat. Postprandial differences in the pancreatic flow rate, electrolytes and total protein were found between both groups. Their origin can be attributed to the protein used (soyabean) in the milk substitute. Such soya protein alters the normal clot formation in the abomasum and allows an accelerated abomasal digesta outflow and duodenal pH alkalinisation.
在出生后的第一个月，哺乳山羊自由采食山羊奶或代乳品。这些日粮在脂肪含量和蛋白质类型上有所不同。比较了两种情况下基础期和对食物反应时外分泌胰腺分泌的成分。在进餐前1小时至餐后第8小时收集胰液。测量胰液流速、碳酸氢盐和氯化物水平、总蛋白和酶活性。在静息状态和对食物的反应中，发现喂食脂肪含量较低的代乳品的组中脂肪酶活性显著较低。这些结果表明酶的输出量与其底物的可利用量相适应，这与在大鼠中所描述的情况类似。两组之间在餐后胰液流速、电解质和总蛋白方面存在差异。其原因可归因于代乳品中使用的蛋白质（大豆）。这种大豆蛋白会改变皱胃中正常的凝块形成，并使皱胃消化物加速流出以及十二指肠pH值碱化。
