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约氏疟原虫同步化:配子体产生、滞留及感染性模式

Synchronized Plasmodium yoelii yoelii: pattern of gametocyte production, sequestration and infectivity.

作者信息

Gautret P, Miltgen F, Chabaud A G, Landau I

机构信息

Laboratoire de Biologie Parasitaire et de Chimiothérapie, CNRS (ERS 156), Paris, France.

出版信息

Parassitologia. 1996 Dec;38(3):575-7.

PMID:9257348
Abstract

The chronobiology of the gametocytes of P. yoelii was studied in Percoll-glucose synchronized infection in the mouse. The gametocyte developmental cycle consisted of 4 successive stages: stage 0 maturation took 27 hours from merozoite invasion, stage 0 to stage 1 lasted 6 hours, stage I to stage II and stage II to stage III lasted 3 hours each. Stage 0 gametocytes were found to sequester in small peripheral capillaries, and the number of oocysts in mosquitoes was related to the number of stage 0 gametocytes ingested.

摘要

在小鼠中,利用Percoll-葡萄糖同步感染法研究了约氏疟原虫配子体的生物钟学。配子体发育周期包括4个连续阶段:从裂殖子侵入开始,0期成熟需27小时,0期到1期持续6小时,1期到2期以及2期到3期各持续3小时。发现0期配子体会滞留于外周小毛细血管中,且蚊子体内卵囊的数量与摄入的0期配子体数量相关。

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