促进对药物治疗方案依从性数据的分析。
Facilitated analysis of data on drug regimen compliance.
作者信息
de Klerk E, van der Linden S, van der Heijde D, Urquhart J
机构信息
Department of Internal Medicine, University Hospital Maastricht, The Netherlands.
出版信息
Stat Med. 1997 Jul 30;16(14):1653-64. doi: 10.1002/(sici)1097-0258(19970730)16:14<1653::aid-sim591>3.0.co;2-#.
Drug actions depend on dose and intervals between doses, in ways that are drug-specific and sometimes complex, complicating the use of drug dosing histories as an explanatory variable in the analysis of clinical trials. We describe a spread-sheet method for conveniently displaying patients' drug dosing histories, to facilitate identification of dosing correlates of clinically important events.
药物作用取决于剂量和给药间隔，其方式具有药物特异性，有时还很复杂，这使得在临床试验分析中使用用药史作为解释变量变得复杂。我们描述了一种电子表格方法，用于方便地展示患者的用药史，以促进识别临床重要事件的给药相关性。
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