Lemaire P, Kodjabachian L
IBDM, Laboratoire de Génétique et Physiologie du Développement, CNRSUMR 9943, Marseille, France.
Trends Genet. 1996 Dec;12(12):525-31. doi: 10.1016/s0168-9525(97)81401-1.
Since the identification of the first organizer gene, goosecoid, more than 15 organizer-specific genes have been characterized. Here, we present our current understanding of the roles of these molecules in amphibians fish and amniotes and show how there identification has confirmed Spemann's original proposition that the vertebrate organizer is subdivided into separate domains: the head, trunk and tail organizers.
自从第一个组织者基因鹅膏蕈氨酸被鉴定以来，已经鉴定出了15种以上的组织者特异性基因。在这里，我们展示了我们目前对这些分子在两栖动物、鱼类和羊膜动物中的作用的理解，并展示了它们的鉴定如何证实了施佩曼最初的观点，即脊椎动物组织者被细分为不同的区域：头部、躯干和尾部组织者。
