Wang Z, Cai J, Wa F, Jin X
Department of Parasitology, Henan Medical University, Zhengzhou, China.
J Egypt Soc Parasitol. 1997 Aug;27(2):529-38.
Seven outbreaks of trichinosis occurred in Zhengzhou (central China) from 1992 to 1996, 250 patients were diagnosed. Trichinella larvae were found in 3 of 4 portions of the pork examined and in 5 of 7 cases by muscle biopsy. There was a higher occurrence of outbreaks in winter. Young and middle-aged workers, cadres and merchants were the majority of patients, (higher in males than in females). The most important clinical manifestations were fever, eyelid edema, tiredness and eosinophilia without any gastrointestinal symptoms, rash and with less myalgia. Anti-Trichinella antibodies were detected by IF in 62.6% individuals with the history of infection. The specific antibodies were only observed in 78% patients one week after onset of disease, while the antibody positive rate was increased to 92.5%, 97.6% and 100% two, three, four and five weeks after the onset and evidently increased from 89.6% before therapy to 100% one week after therapy, and decreased to 74.6% and 23.7% one and four months after therapy respectively, which suggested that IF was a useful tool for immunodiagnosis and checking up therapeutic effect of trichinosis.
1992年至1996年期间，中国中部的郑州市发生了7起旋毛虫病疫情，确诊患者达250例。在所检查的4份猪肉中，有3份检出旋毛虫幼虫，在7例患者中，有5例通过肌肉活检发现了幼虫。冬季疫情发生率较高。患者以中青年工人、干部和商人为多，男性多于女性。最重要的临床表现为发热、眼睑水肿、乏力和嗜酸性粒细胞增多，无任何胃肠道症状、皮疹，肌痛较少。在有感染史的个体中，62.6%通过间接免疫荧光法检测到抗旋毛虫抗体。发病一周后，仅78%的患者检测到特异性抗体，而发病两周、三周、四周和五周后，抗体阳性率分别升至92.5%、97.6%和100%，治疗前抗体阳性率为89.6%，治疗一周后明显升至100%，治疗后一个月和四个月分别降至74.6%和23.7%，这表明间接免疫荧光法是旋毛虫病免疫诊断和疗效检查的有效手段。
