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Synthesis and biology of a 7-nitro-2,1,3-benzoxadiazol-4-yl derivative of 2-phenylindole-3-acetamide: a fluorescent probe for the peripheral-type benzodiazepine receptor.

作者信息

Kozikowski A P, Kotoula M, Ma D, Boujrad N, Tückmantel W, Papadopoulos V

机构信息

Drug Discovery Laboratory, Georgetown University Medical Center, Washington, D.C. 20007, USA.

出版信息

J Med Chem. 1997 Aug 1;40(16):2435-9. doi: 10.1021/jm970220w.

DOI:10.1021/jm970220w
PMID:9258348
Abstract
摘要

相似文献

1
Synthesis and biology of a 7-nitro-2,1,3-benzoxadiazol-4-yl derivative of 2-phenylindole-3-acetamide: a fluorescent probe for the peripheral-type benzodiazepine receptor.2-苯基吲哚-3-乙酰胺的7-硝基-2,1,3-苯并恶二唑-4-基衍生物的合成与生物学性质:一种外周型苯二氮卓受体荧光探针
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2
N-benzyl-2-(6,8-dichloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-N-(6-(7-nitrobenzo[c][1,2,5]oxadiazol-4-ylamino)hexyl)acetamide as a new fluorescent probe for peripheral benzodiazepine receptor and microglial cell visualization.N-苄基-2-(6,8-二氯-2-(4-氯苯基)咪唑并[1,2-a]吡啶-3-基)-N-(6-(7-硝基苯并[c][1,2,5]恶二唑-4-基氨基)己基)乙酰胺作为一种用于外周苯二氮䓬受体和小胶质细胞可视化的新型荧光探针。
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Pyruvate dehydrogenase interactions with peripheral-type benzodiazepine receptors.丙酮酸脱氢酶与外周型苯二氮䓬受体的相互作用。
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Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human esophageal cancer cells.外周苯二氮䓬受体的特异性配体可诱导人食管癌细胞凋亡并使细胞周期停滞。
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Synthesis and biochemical characterization of two novel irreversible ligands specific for "peripheral" benzodiazepine receptors.两种新型不可逆配体的合成及其对“外周”苯二氮䓬受体特异性的生化特性研究
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Novel irreversible fluorescent probes targeting the 18 kDa translocator protein: synthesis and biological characterization.新型靶向 18kDa 转位蛋白的不可逆荧光探针:合成与生物学特性。
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New fluorescent 2-phenylindolglyoxylamide derivatives as probes targeting the peripheral-type benzodiazepine receptor: design, synthesis, and biological evaluation.新型荧光2-苯基吲哚乙二酰胺衍生物作为靶向外周型苯二氮䓬受体的探针:设计、合成及生物学评价
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Characterization of porphyrin interactions with peripheral type benzodiazepine receptors.卟啉与外周型苯二氮䓬受体相互作用的表征
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Peripheral benzodiazepine induces morphological changes and proliferation of mitochondria in glioma cells.外周苯二氮䓬类药物可诱导胶质瘤细胞中线粒体的形态变化和增殖。
J Neurosci Res. 1991 Nov;30(3):463-74. doi: 10.1002/jnr.490300303.
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Central- and peripheral-type benzodiazepine receptors.中枢型和外周型苯二氮䓬受体。
Adv Biochem Psychopharmacol. 1986;41:1-10.

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