Gnarpe H, Gnarpe J, Gästrin B, Hallander H
Department of Clinical Microbiology, Gävle Central Hospital, Sweden.
Scand J Infect Dis Suppl. 1997;104:50-2.
Sera from 20 male patients with a diagnosis suggestive of myocarditis, perimyocarditis or pericarditis were found significantly more often to have specific IgA antibodies to Chlamydia pneumoniae than sera from healthy blood donors of the same age and from the same time period. A less pronounced difference in IgG titres was found between patients and blood donors, and IgM antibodies were found only in one patient. A striking variation over time in the prevalence of specific antibodies to C. pneumoniae was seen in consecutive male blood donors over a 5-year observation period. The findings were discussed and it was concluded that C. pneumoniae may be associated with inflammatory heart disease.
诊断提示为心肌炎、心肌心包炎或心包炎的20名男性患者的血清中，与同期相同年龄的健康献血者血清相比，更常发现有针对肺炎衣原体的特异性IgA抗体。患者与献血者之间IgG滴度的差异不太明显，仅在一名患者中发现IgM抗体。在5年观察期内，连续的男性献血者中，针对肺炎衣原体的特异性抗体患病率随时间有显著变化。对这些发现进行了讨论，并得出结论：肺炎衣原体可能与炎症性心脏病有关。
