Vincent P G, Bare C E, Gentner W A
J Pharm Sci. 1977 Dec;66(12):1716-9. doi: 10.1002/jps.2600661215.
Approximately 200 accessions of Papaver species were evaluated for identification as P. bracteatum Lindl. and for thebaine content. Fifteen authentic P. bracteatum accessions were selected on the basis of chromosome count. Statistical analyses of variation in alkaloid content were made for these accessions. Four of the 15 warranted further study based on the vigor of the plant and the total thebaine present in the tissue. Significant variability in thebaine content was found in wild strains of P. bracteatum, thus requiring genetic selection studies. The data showed that total yield potential of thebain should be considered in selecting P. bracteatum strains for commercial growth rather than concentrating on strains that produce the highest thebaine concentrations. A method for the quantitative estimation of thebaine from P. bracteatum is presented.
对约200份罂粟属物种材料进行了鉴定,以确定其是否为苞叶罂粟(Papaver bracteatum Lindl.)并检测蒂巴因含量。根据染色体计数,挑选出15份纯正的苞叶罂粟材料。对这些材料的生物碱含量变异进行了统计分析。基于植株活力和组织中总蒂巴因含量,15份材料中有4份值得进一步研究。在苞叶罂粟的野生菌株中发现了蒂巴因含量的显著变异性,因此需要进行遗传选择研究。数据表明,在选择用于商业种植的苞叶罂粟菌株时,应考虑蒂巴因的总产量潜力,而不是专注于产生最高蒂巴因浓度的菌株。本文介绍了一种从苞叶罂粟中定量估算蒂巴因的方法。