Transcriptional control: calling in histone deacetylase.
作者信息
Kiermaier A, Eilers M
机构信息
Zentrum für Molekulare Biologie, Heidelberg, Germany.
出版信息
Curr Biol. 1997 Aug 1;7(8):R505-7. doi: 10.1016/s0960-9822(06)00249-1.
PMID:9259549
Abstract
Mad proteins are transcriptional repressors that antagonize transcriptional activation and transformation by Myc oncoprotein; recent findings suggest that they repress transcription by recruiting histone deacetylases to target sites on DNA.
摘要
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