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Successful use of the cell separator hemonetics multicomponent collection system+ for therapeutic thrombocytapheresis in a low body weight child of essential thrombocythemia.

作者信息

Singh Abhay, Nityanand Soniya, Sonker Atul, Kumar Sanjeev

机构信息

Department of Transfusion Medicine, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

出版信息

Asian J Transfus Sci. 2015 Jul-Dec;9(2):207-9. doi: 10.4103/0973-6247.162722.

DOI:10.4103/0973-6247.162722
PMID:26420947
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4562148/
Abstract

In children, essential thrombocythemia (ET) is extremely rare with an incidence of 1/million. Since thromboembolic complications are more common than hemorrhagic manifestation, immediate thromboctyapheresis by an automated cell separator can prevent untoward consequences in the form of cerebrovascular, coronary or peripheral vascular occlusive events. Due to varied options of automated cell separators, selecting an appropriate cell separator in such acute emergency situation can be confusing for a treating physician, especially if the patient is a child of low body weight. We present here the successful use of hemonetics multicomponent collection system (MCS+) for therapeutic platelet reduction (TPR) in a 12-year-old male child of 28 kg with extreme thrombocytosis (TS) (3072 × 10(9)/l) due to ET. A total of three procedures were performed without priming of the machine with allogenic blood. We observed hemonetics MCS+, best suited for TPR even in children with low body weight.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210e/4562148/aef0a170fb1b/AJTS-9-207-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210e/4562148/aef0a170fb1b/AJTS-9-207-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210e/4562148/aef0a170fb1b/AJTS-9-207-g002.jpg

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本文引用的文献

1
Successful management of acute bleeding in essential thrombocythemia using automated cell separator.使用自动细胞分离器成功管理原发性血小板增多症的急性出血。
Transfus Apher Sci. 2014 Feb;50(1):56-8. doi: 10.1016/j.transci.2013.07.035. Epub 2013 Nov 28.
2
Thrombocytapheresis: managing essential thrombocythemia in a surgical patient.血小板分离术:在手术患者中治疗原发性血小板增多症。
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成人及儿童血小板增多症诊治指南
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Thrombocytosis in childhood.儿童血小板增多症。
Indian Pediatr. 2008 Aug;45(8):669-77.
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