Ploeckinger B, Ulm M R, Chalubinski K
Department of Prenatal Diagnosis and Therapy, University of Vienna, Austria.
Am J Perinatol. 1997 Feb;14(2):99-101. doi: 10.1055/s-2007-994106.
Ehlers-Danlos syndrome type II is a rare connective tissue disorder with unknown pregnancy-related maternal and fetal morbidity. The course and outcome of pregnancy in a primigravid woman with Ehlers-Danlos syndrome type II is described. At 17 weeks' gestation a prophylactic Shirodkar cerclage was performed without complications. From the 29th week on, decreased blood flow of the umbilical artery was measured, and fetal growth retardation was evident from 34 weeks' gestation on. Pregnancy ended at 41 weeks by spontaneous vaginal delivery of a healthy 2900-g female infant. Previous reports of 16 women with Ehlers-Danlos syndrome type II, who had a total of 24 pregnancies, are reviewed.
II型埃勒斯-当洛综合征是一种罕见的结缔组织疾病，与妊娠相关的母体和胎儿发病率尚不清楚。本文描述了一名患有II型埃勒斯-当洛综合征的初孕妇的妊娠过程和结局。妊娠17周时进行了预防性希罗德卡尔宫颈环扎术，无并发症。从第29周开始，测量到脐动脉血流减少，妊娠34周起胎儿生长受限明显。妊娠41周时通过自然阴道分娩一名健康的2900克女婴，妊娠结束。本文回顾了先前报道的16名患有II型埃勒斯-当洛综合征的女性，她们总共怀孕24次。
