间皮瘤监测以确定石棉暴露源。
Mesothelioma surveillance to locate sources of exposure to asbestos.
作者信息
Teschke K, Morgan M S, Checkoway H, Franklin G, Spinelli J J, van Belle G, Weiss N S
机构信息
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada.
出版信息
Can J Public Health. 1997 May-Jun;88(3):163-8. doi: 10.1007/BF03403881.
To determine whether there were previously unrecognized sources of asbestos exposure in British Columbia, incident mesothelioma cases (n = 51) and population-based controls (n = 154) were interviewed about their occupational histories and asbestos exposures. The following occupations were at elevated risk: sheet metal workers (OR = 9.6, 95% CI: 1.5-106), plumbers and pipefitters (OR = 8.3, 95% CI: 1.5-86), shipbuilding workers (OR = 5.0, 95% CI: 1.2-23), painters (OR = 4.5, 95% CI: 1.0-24), welders (OR = 3.9, 95% CI: 0.8-22), gardeners (OR = 3.9, 95% CI: 0.8-22), bricklayers (OR = 3.5, 95% CI: 0.9-14), miners (OR = 3.4, 95% CI: 0.9-13), machinists (OR = 3.2, 95% CI: 1.0-11), construction foremen (OR = 3.1, 95% CI: 0.9-11), and electricians (OR = 3.0, 95% CI: 0.8-12). In a reanalysis excluding subjects who worked in occupations or processes considered strongly a priori at risk, three groups remained of interest: non-asbestos miners (OR = 9.6, 95% CI: 1.8-53), bricklayers (OR = 5.4, 95% CI: 1.0-28), and construction labourers (OR = 2.8, 95% CI: 0.7-10.6).
为确定不列颠哥伦比亚省是否存在此前未被识别的石棉暴露源，研究人员就职业史和石棉暴露情况对间皮瘤确诊病例（n = 51）和基于人群的对照者（n = 154）进行了访谈。以下职业的风险较高：钣金工（比值比[OR] = 9.6，95%置信区间[CI]：1.5 - 106）、水管工和管道装配工（OR = 8.3，95% CI：1.5 - 86）、造船工人（OR = 5.0，95% CI：1.2 - 23）、油漆工（OR = 4.5，95% CI：1.0 - 24）、焊工（OR = 3.9，95% CI：0.8 - 22）、园艺工人（OR = 3.9，95% CI：0.8 - 22）、瓦工（OR = 3.5，95% CI：0.9 - 14）、矿工（OR = 3.4，95% CI：0.9 - 13）、机械师（OR = 3.2，95% CI：1.0 - 11）、建筑工头（OR = 3.1，95% CI：0.9 - 11）以及电工（OR = 3.0，95% CI：0.8 - 12）。在一项排除了从事被认为先验风险极高的职业或工作流程的受试者的重新分析中，仍有三组值得关注：非石棉矿工（OR = 9.6，95% CI：1.8 - 53）、瓦工（OR = 5.4，95% CI：1.0 - 28）以及建筑工人（OR = 2.8，95% CI：0.7 - 10.6）。
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