展毛银柴胡苷C和D，来自展毛银柴胡的具有生物活性的酰化三萜皂苷。

Jennisseensosides C and D, biologically active acylated triterpene saponins from Silene jenisseensis.

作者信息

Lacaille-Dubois M A, Hanquet B, Cui Z H, Lou Z C, Wagner H

机构信息

Laboratoire de Pharmacognosie, Université de Bourgogne, Dijon, France.

出版信息

Phytochemistry. 1997 Jul;45(5):985-90. doi: 10.1016/s0031-9422(97)00087-3.

DOI:10.1016/s0031-9422(97)00087-3

PMID:9264608

Abstract

We previously reported the isolation and structure elucidation of a new trans-p-methoxycinnamoyl triterpene-saponin along with its cis-p-methoxycinnamoyl isomer as an inseparable mixture from the roots of Silene jenisseensis. In a continuing study on this plant, two additional new acylated triterpene-saponins were obtained as an inseparable mixture. Their structures have been established by chemical means and spectroscopic methods including 1D and 2D homonuclear and heteronuclear correlation NMR spectroscopy as 3-O-[beta-D-galactopyranosyl-(1-->2)-beta-D-glucuronopyranosyl]-28 -O-[{alpha-L-rhamnopyranosyl-(1-->2)}-{4-O-trans-p-methoxycinnamoyl++ +}-beta-D-fucopyranosyl] quillaic acid and its cis-isomer, respectively. They showed a significant enhancement of the granulocyte phagocytosis in vitro.

摘要

我们之前报道过从叉枝蝇子草的根部中分离并鉴定出一种新的反式对甲氧基肉桂酰基三萜皂苷及其顺式对甲氧基肉桂酰基异构体，它们是一种不可分离的混合物。在对该植物的持续研究中，又得到了两种新的酰化三萜皂苷，它们也是不可分离的混合物。通过化学方法和光谱学方法，包括一维和二维同核及异核相关核磁共振光谱，确定了它们的结构，分别为3-O-[β-D-吡喃半乳糖基-(1→2)-β-D-吡喃葡萄糖醛酸基]-28-O-[{α-L-吡喃鼠李糖基-(1→2)}-{4-O-反式对甲氧基肉桂酰基}-β-D-吡喃岩藻糖基]齐墩果酸及其顺式异构体。它们在体外显示出显著增强粒细胞吞噬作用的效果。