Chandra Satish, Rawat D S
Department of Biological Sciences, College of Basic Science & Humanities, Govind Ballabh Pant University of Agriculture and Technology Pantnagar, Pantnagar, India.
Integr Med Res. 2015 Sep;4(3):123-131. doi: 10.1016/j.imr.2015.06.004. Epub 2015 Jul 4.
Several species of the family Caryophyllaceae are widely used by many ethnic communities as traditional medicine throughout the world. The highest number of plants of the family are used in Chinese traditional medicine. The ethnopharmacologial studies of this family indicate that plants of the family possess anticancer, antibacterial, antifungal, antiviral, antioxidant, and anti-inflammatory properties. Other miscellaneous properties reported are ribosome inactivation properties, inhibition of prostatic enlargement in rats, and inhibition of intestinal enzyme carboxyelasterase in rats, cerebro-protective activity, and antiobesity in rats. Few reviews have been published yet, providing information regarding medicinal plants of the family and their biomedical properties. All published reviews have focused either on a particular taxa or a few species. The present review is focused on the traditional medicinal uses of the plants of the family Caryophyllaceae along with phytochemical and pharmacological studies of the family. A study of the literature revealed significant traditional medicinal importance of the family. Major chemical constituents of Caryophyllceae are saponins, Phytoecdysteroids, benzenoids, phenyl propanoids, and nitrogen containing compounds. The most important property of plants of the family is anticancer activity and is shown by the large number of plant species studied. This review of traditional medicinal and pharmacological uses of plants of the family, provide a ground for future research in the family.
石竹科的几个物种在世界各地被许多民族社区广泛用作传统药物。该科植物在中国传统医学中的应用最为广泛。对该科的民族药理学研究表明，该科植物具有抗癌、抗菌、抗真菌、抗病毒、抗氧化和抗炎特性。报道的其他杂项特性包括核糖体失活特性、对大鼠前列腺增生的抑制作用、对大鼠肠道酶羧基酯酶的抑制作用、脑保护活性以及对大鼠的抗肥胖作用。目前关于该科药用植物及其生物医学特性的综述较少。所有已发表的综述都集中在特定的分类群或少数物种上。本综述重点关注石竹科植物的传统药用用途以及该科的植物化学和药理学研究。对文献的研究揭示了该科在传统医学中的重要意义。石竹科的主要化学成分是皂苷、植物蜕皮甾类、苯类化合物、苯丙素类和含氮化合物。该科植物最重要的特性是抗癌活性，大量研究的植物物种都显示出这一特性。对该科植物传统药用和药理学用途的综述为该科未来的研究奠定了基础。
