Katargina L A, Slepova O S, Krichevskaia G I, Khvatova A V, Bykovskaia G N
Moscow NII of Eye Diseases.
Vestn Oftalmol. 1997 May-Jun;113(3):23-6.
Sixty-eight children with peripheral uveitis (PU) were examined, which is 11.5% of the total number of children with endogenous uveitis. In addition to the classical signs of PU, children often develop papillitis, corneal precipitations, and diffuse cataracts which are formed early. Clinical and immunological correlations were revealed, indicating a relationship between the clinical features and the disease etiology and pathogenesis: herpetic forms of PU (infectious and infectious-allergic) with immunopathological reactions to the retinal S-antigen only during late stages when the process takes a chronic course. Differentiated treatment strategy of PU with due consideration for the detected features is proposed.
对68例周边葡萄膜炎(PU)患儿进行了检查,占内因性葡萄膜炎患儿总数的11.5%。除了PU的典型体征外,患儿常出现视乳头炎、角膜后沉着物和早期形成的弥漫性白内障。揭示了临床与免疫学的相关性,表明临床特征与疾病病因及发病机制之间的关系:PU的疱疹形式(感染性和感染过敏性)仅在病程呈慢性的晚期出现对视网膜S抗原的免疫病理反应。提出了考虑到所检测特征的PU差异化治疗策略。