与顺铂给药相关的癫痫发作。
Seizures associated with cisplatin administration.
作者信息
Brauers A, Mattelaer P, Mersdorf A, Wang J, Jakse G
机构信息
Department of Urology, Medical Faculty, Technical University, Aachen, Germany.
出版信息
Eur Urol. 1997;32(1):118-20.
PMID:9266243
Abstract
A 50-year-old patient with a diagnosis of a primary extragonadal germ cell tumor received cisplatin-containing polychemotherapy and developed seizures after the first course of drug administration. We discuss this very rare toxic side effect of cisplatin and present a review of the literature concerning the experience with neurotoxic effects exerted by this agent.
摘要
一名被诊断为原发性性腺外生殖细胞肿瘤的50岁患者接受了含顺铂的多药化疗，在首次给药疗程后出现癫痫发作。我们讨论顺铂这种非常罕见的毒副作用，并对有关该药物神经毒性作用经验的文献进行综述。
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