Lin M T, Nguyen B T, Binh T V, Be T V, Chiang T Y, Tseng L H, Yang Y C, Lin K H, Chen Y C
Department of Oncology, Blood Transfusion Hematology Center, Ho Chi Minh City, Vietnam.
Arch Virol. 1997;142(7):1429-40.
Anti-human T-lymphotropic virus type I/II (HTLV-I/II) antibodies were screened by particle agglutination test in a total of 66 patients with thalassemia major who received multiple transfusion from paid donors at the Blood Transfusion Hematology Center of Ho Chi Minh City in South Vietnam. HTLV-II infection was confirmed in 6 patients (9.1%) by Western blot analysis and/or polymerase chain reaction. Phylogenetic analysis revealed that long terminal repeat sequences of HTLV-II proviruses from 5 thalassemic patients in Vietnam belonged to the same phylogenetic subgroup of HTLV-IIb as those from intravenous drug abusers in North America and Europe. These data shed light on the route of introducing HTLV-II into Vietnam.
在越南南部胡志明市输血血液学中心，对66例重型地中海贫血患者进行了抗人I/II型嗜人T淋巴细胞病毒（HTLV-I/II）抗体筛查，这些患者接受了来自有偿供血者的多次输血。通过蛋白质印迹分析和/或聚合酶链反应，在6例患者（9.1%）中确诊为HTLV-II感染。系统发育分析显示，越南5例地中海贫血患者的HTLV-II前病毒长末端重复序列与北美和欧洲静脉吸毒者的序列属于HTLV-IIb的同一系统发育亚组。这些数据为HTLV-II传入越南的途径提供了线索。
