Feldmann R, Löw-Weiser H, Duschet P, Gschnait F
Department of Dermatology, Krankenhaus der Stadt Wien-Lainz, Austria.
Dermatology. 1997;195(1):52-3. doi: 10.1159/000245687.
We report a patient with multiple sclerosis who was receiving subcutaneous injections of recombinant interferon beta. During the third month of treatment, painful necrotizing cutaneous lesions appeared at the injection sites. The possible pathogenesis of interferon-induced skin necrosis is discussed.
我们报告了一名正在接受重组β干扰素皮下注射的多发性硬化症患者。在治疗的第三个月，注射部位出现了疼痛性坏死性皮肤病变。文中讨论了干扰素诱导皮肤坏死的可能发病机制。
