Sobaniec-Lotowska M, Sobaniec W, Sulkowska M, Sulkowski S, Kułak W
Zakładu Anatomii Patologicznej AM w Białymstoku.
Pol Merkur Lekarski. 1996 Nov;1(5):334-6.
An incidence and morphology of the CNS congenital malformations in newborn babies and infants were analysed in the consecutive autopsies carried out in 1986-1990, i.e. following Tscharnobyl disaster. The obtained results were compared to those seen in the two earlier periods (1976-1980 and 1981-1986). In 1986-1990, a percentage of autopsies showing congenital CNS malformations increased approximately by two-fold (15%). The highest percentage of such malformations in specific years of the analysed period was noted in 1990 (20%). Central nervous system malformations were more frequent in female sex (57%) than in male sex (43%). In 64% of cases newborn babies were affected. A percentage of CNS malformations coexisting with other congenital malformations increased to 40% in the analysed period of time (from 29.4% in 1976-1985). Meningomyelocele (41%), congenital hydrocephalus (21.5%), multiple anomalies in brain (14%), and anencephaly (12.6%) constituted the most frequent group of CNS malformations. In 1986-1990, an incidence of meningomyelocele increased by more than two-fold (if this anomaly coexisted with hydrocephaly, an increase in the incidence exceeded three-fold), and hydrocephaly as well as an increase in the incidence of anencephaly by 1.5 times in comparison with 1976-1985.
对1986 - 1990年(即切尔诺贝利灾难之后)连续进行的新生儿和婴儿尸检中中枢神经系统先天性畸形的发病率和形态进行了分析。将所得结果与之前两个时期(1976 - 1980年和1981 - 1986年)的结果进行了比较。1986 - 1990年,显示先天性中枢神经系统畸形的尸检百分比增加了约两倍(15%)。在分析期的特定年份中,此类畸形的最高百分比出现在1990年(20%)。中枢神经系统畸形在女性中更为常见(57%),而在男性中为(43%)。在64%的病例中,新生儿受到影响。在分析期内,与其他先天性畸形共存的中枢神经系统畸形百分比增加到40%(从1976 - 1985年的29.4%)。脊髓脊膜膨出(41%)、先天性脑积水(21.5%)、脑多发性畸形(14%)和无脑儿(12.6%)构成了最常见的中枢神经系统畸形组。与1976 - 1985年相比,1986 - 1990年脊髓脊膜膨出的发病率增加了两倍多(如果这种畸形与脑积水共存,发病率增加超过三倍),脑积水以及无脑儿的发病率增加了1.5倍。