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[华沙大气尘埃的诱变活性]

[Mutagenic activity of atmospheric dust in Warsaw].

作者信息

Krogulski A, Borkowska M, Strusiński A

机构信息

Zakład Higieny Komunalnej, Państwowy Zakład Higieny, Warszawa.

出版信息

Rocz Panstw Zakl Hig. 1997;48(1):31-5.

PMID:9273661
Abstract

The results are presented of the studies of the mutagenic activity of dust samples in atmospheric air in Warsaw in the heating and non-heating seasons. Dust samples were obtained with a Staplex-type device continuously during 24 hours. The dust collected on the filters was extracted with cyclohexane. The devaporized and dried extract, that is the so called tar substances, were the material for further studies. The mutagenic activity of the studied samples was determined using a modification of the test of somatic mutation and recombination (SMART) on Drosophila melanogaster. The cross-bred strain mwh x ORR: flr3/TM3, Ser specially prepared for the research of WAA was used. The dust in atmospheric air of Warsaw showed mutagenic activity which was higher in samples taken in the heating season.

摘要

给出了华沙大气空气中粉尘样品在供暖季和非供暖季致突变活性的研究结果。使用Staplex型设备在24小时内连续采集粉尘样品。滤膜上收集的粉尘用环己烷萃取。蒸发并干燥后的提取物,即所谓的焦油物质,作为进一步研究的材料。采用对黑腹果蝇体细胞突变和重组试验(SMART)的改进方法来测定所研究样品的致突变活性。使用专门为大气空气中粉尘研究准备的杂交品系mwh x ORR: flr3/TM3, Ser。华沙大气空气中的粉尘表现出致突变活性,且在供暖季采集的样品中活性更高。

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