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Involvement of the claustrum in the convulsive evolution of temporal limbic seizure in feline amygdaloid kindling.

作者信息

Wada J A, Kudo T

机构信息

Division of Neurosciences, University of British Columbia, Vancouver, Canada.

出版信息

Electroencephalogr Clin Neurophysiol. 1997 Aug;103(2):249-56. doi: 10.1016/s0013-4694(97)96160-5.

DOI:10.1016/s0013-4694(97)96160-5
PMID:9277628
Abstract

The effects of unilateral lesioning of the claustrum (CL) either prior to or following completion of amygdaloid (AM) kindling was examined in cats. CL lesioning ipsilateral to the kindling or the kindled AM caused the emergence of a mirror image pattern of expected or established AM onset convulsive seizure originating in the contralateral hemisphere. This finding suggests that: (1) the CL is involved in the convulsive evolution of AM onset non-convulsive limbic seizure; (2) an alternative transhemispheric route is available for the convulsive evolution of AM onset limbic seizure when the ipsilateral CL is disrupted; and (3) the CL is not critical for secondary convulsive generalization.

摘要

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