Albu J, Shur M, Curi M, Murphy L, Heymsfield S B, Pi-Sunyer F X
Department of Medicine, Obesity Research Center, St Luke's-Roosevelt Hospital Center and Columbia University College of Physicians and Surgeons, New York, NY 10025, USA.
Am J Clin Nutr. 1997 Sep;66(3):531-8. doi: 10.1093/ajcn/66.3.531.
In the United States, obesity is more prevalent in black than in non-Hispanic white women. Because low resting metabolic rate (RMR) has been suggested as a risk factor for weight gain, we compared RMR in 22 black and 20 white obese [body mass index (BMI; in kg/m2) range: 28.9-48.6 and 26.9-44.1, respectively], weight-stable, premenopausal, nondiabetic women. RMR was measured on two or three different occasions within a 1-wk period. The black and white groups did not differ significantly in age, degree of fitness, BMI, fat mass, or fat-free mass (FFM). In each group, RMR was predicted independently by FFM but not by age, degree of fitness, body fat mass, or body fat distribution. The slopes of the equations predicting RMR from FFM in black and white groups were not significantly different. However, the black women had significantly lower RMRs than the white women after adjustment for FFM measured by five body-composition models: dual-photon X-ray absorptiometry (DXA), hydrodensitometry, total body water, a three-compartment model, a four-compartment model, as well as for the absolute total-body potassium content as a measure of metabolically active FFM. By each analysis, the black women had significantly lower (P < 0.01) FFM-adjusted RMR than the white women; this difference ranged from 671 to 889 kJ/d depending on the body-composition method used to estimate FFM. This could contribute to the difference in the prevalence of obesity in the populations represented by these groups.
在美国，肥胖在黑人女性中比在非西班牙裔白人女性中更为普遍。由于低静息代谢率（RMR）被认为是体重增加的一个风险因素，我们比较了22名黑人肥胖女性和20名白人肥胖女性[体重指数（BMI；单位：kg/m²）范围分别为28.9 - 48.6和26.9 - 44.1]的RMR，这些女性体重稳定、处于绝经前且非糖尿病患者。在1周内的两到三个不同时间测量RMR。黑人和白人组在年龄、健康程度、BMI、脂肪量或去脂体重（FFM）方面没有显著差异。在每组中，RMR由FFM独立预测，而非由年龄、健康程度、体脂肪量或体脂肪分布预测。黑人和白人组中由FFM预测RMR的方程斜率没有显著差异。然而，在通过五种身体成分模型测量的FFM进行调整后，黑人女性的RMR显著低于白人女性，这五种模型分别是双能X线吸收法（DXA）、水下密度测量法、总体水、三室模型、四室模型，以及作为代谢活跃FFM指标的绝对全身钾含量。通过每项分析，黑人女性经FFM调整后的RMR均显著低于白人女性（P < 0.01）；根据用于估计FFM的身体成分方法不同，这种差异在671至889 kJ/d之间。这可能导致这些群体所代表的人群中肥胖患病率的差异。
