Hira N K, Marciniak M M, Penner S L
DVA West Side Medical Center, Chicago, Illinois 60680, USA.
J Am Optom Assoc. 1997 Jul;68(7):452-8.
Ophthalmomyiasis is ocular invasion by a fly larva. In the United States, only two cases of bilateral subretinal ophthalmomyiasis have been reported in the literature. Subretinal invasion by the fly larva results in characteristic ophthalmoscopic and angiographic findings. Recently, similar subretinal changes have been associated with amyotrophic lateral sclerosis/Parkinsonism dementia complex (ALS-PDC) in the Chamorro population of Guam. This pigmentary retinopathy of Guam (PROG) is generally bilateral in presentation, whereas ophthalmomyiasis is generally unilateral. While PROG has been associated with neurologic findings, ophthalmomyiasis interna posterior (OIP) has not.
A case of a 65-year-old Asian man with bilateral subretinal changes is described. Similarities and differences between ophthalmomyiasis and the pigmentary retinopathy of Guam are discussed.
Because PROG has been associated with ALS-PDC, a neurologic evaluation should be included in the workup of patients suspected of having OIP or PROG.
眼蝇蛆病是蝇幼虫对眼部的侵袭。在美国，文献中仅报道过两例双侧视网膜下眼蝇蛆病病例。蝇幼虫的视网膜下侵袭会导致特征性的眼底镜和血管造影表现。最近，在关岛的查莫罗人群中，类似的视网膜下改变与肌萎缩侧索硬化症/帕金森病痴呆综合征（ALS-PDC）有关。关岛的这种色素性视网膜病变（PROG）通常表现为双侧，而眼蝇蛆病通常为单侧。虽然PROG与神经系统表现有关，但眼内后蝇蛆病（OIP）并非如此。
描述了一例65岁亚洲男性双侧视网膜下改变的病例。讨论了眼蝇蛆病与关岛色素性视网膜病变之间的异同。
由于PROG与ALS-PDC有关，对于疑似患有OIP或PROG的患者，检查应包括神经系统评估。
