Fasching P
Klinische Abtellung für Endokrinologie und Stoffwechsel, Universitäts-klinik für Innere Medizin III, Wien.
Wien Med Wochenschr. 1997;147(9):217-21.
Pregnant type-I diabetic women have to be treated in an experienced diabetes center where optimal cooperation and exchange of knowledge between obstetrician, diabetologist and neonatologist is guaranteed. Given optimal preconceptional metabolic control and thorough guidance throughout pregnancy maternal and fetal risk of type-I diabetic patients without severe diabetic late complications is similar to that of healthy pregnant women. "Near-normoglycemic" metabolic control and meticulous prevention of severe and long-standing hypoglycemic episodes can be achieved throughout pregnancy by functional insulin therapy employing a basis-bolus regime of insulin administration with frequent blood glucose self control (more than 6 times a day). Non-compliant diabetic patients and those with severe diabetic late complications represent a high-risk group for complications in pregnancy. To avoid such risks special care and preconceptional information is mandatory.
患有I型糖尿病的孕妇必须在经验丰富的糖尿病中心接受治疗，该中心要确保产科医生、糖尿病专家和新生儿科医生之间能进行最佳的合作与知识交流。如果孕前代谢得到最佳控制，并在整个孕期得到全面指导，没有严重糖尿病晚期并发症的I型糖尿病患者的母婴风险与健康孕妇相似。通过采用基础-餐时胰岛素给药方案并频繁进行血糖自我监测（每天超过6次）的功能性胰岛素治疗，在整个孕期可以实现“接近正常血糖”的代谢控制，并精心预防严重和长期的低血糖发作。不依从治疗的糖尿病患者以及患有严重糖尿病晚期并发症的患者是妊娠并发症的高危人群。为避免此类风险，必须提供特殊护理和孕前信息。
