Di Toro A, Marotta A, Todisco N, Ponticiello E, Collini R, Di Lascio R, Perrone L
Department of Pediatrics of 2nd University of Naples, Italy.
Biol Trace Elem Res. 1997 May;57(2):97-104. doi: 10.1007/BF02778192.
Serum iron (sFe), and ferritin (sFert), transferrin saturation index (TSI), plasma zinc and copper (pZn, pCu), and erythrocyte zinc content (eZn) were measured in 55 obese children and adolescents (28 males and 27 females) before and after a 13-wk treatment with a hypocaloric balanced diet (HCBD, 22 subjects) or a 10-wk treatment with a protein sparing modified fast diet (PSMF, 33 subjects). The energy intake provided by the HCBD and PSMF diet was calculated to be 60 and 25%, respectively, of the recommended dietary allowances (RDAs) for age and sex. Neither diet was supplemented with trace elements or calcium. Using a visual memory system, all subjects had a 24-h dietary intake recall before starting the weight-loss program. Iron, zinc, and copper intakes from the 24-h recall were compared with those from prescribed diets. Both diets produced a significant (p < 0.001) weight reduction with a significant reduction in the arm muscle area of the PSMF group. After treatment, no significant change was observed in sFe, sFert, and TSI of either group, whereas eZn increased significantly in the HCBD and the PSMF groups (p = 0.001 and p < 0.006, respectively), with an improvement of the erythrocyte index (E.I.). A significant increase in pZn was also observed in the PSMF group (p = 0.007).
对55名肥胖儿童和青少年（28名男性和27名女性）进行了血清铁（sFe）、铁蛋白（sFert）、转铁蛋白饱和度指数（TSI）、血浆锌和铜（pZn、pCu）以及红细胞锌含量（eZn）的测量。这些儿童和青少年分别接受了为期13周的低热量均衡饮食（HCBD，22名受试者）治疗或为期10周的蛋白质节省改良禁食饮食（PSMF，33名受试者）治疗。经计算，HCBD和PSMF饮食提供的能量摄入量分别为年龄和性别推荐膳食摄入量（RDA）的60%和25%。两种饮食均未补充微量元素或钙。在开始减肥计划前，所有受试者均使用视觉记忆系统进行了24小时饮食摄入量回忆。将24小时回忆中的铁、锌和铜摄入量与规定饮食中的摄入量进行了比较。两种饮食均使体重显著减轻（p<0.001），PSMF组的手臂肌肉面积也显著减小。治疗后，两组的sFe、sFert和TSI均未观察到显著变化，而HCBD组和PSMF组的eZn均显著增加（分别为p = 0.001和p<0.006），红细胞指数（E.I.）有所改善。PSMF组的pZn也显著增加（p = 0.007）。
