Ghosh S, Meister D, Cowen S, Hannan W J, Ferguson A
Department of Medicine, University of Edinburgh, UK.
Eur J Gastroenterol Hepatol. 1997 Aug;9(8):783-8. doi: 10.1097/00042737-199708000-00009.
To evaluate the use of an inexpensive hand-held bioelectric impedance analysis machine which measures lean body mass, by technical comparisons against standard instruments and techniques (an in-house bioelectric impedance machine and dual energy X-ray absorptiometry), and by performing body composition analyses in groups of potentially malnourished patients.
Prospective simultaneous comparison of measurements made by the hand-held and in-house bioelectric analysis machines and dual energy x-ray absorptiometry.
Medical Physics Department and Gastrointestinal Unit in a university teaching hospital.
SUBJECTS/METHODS: One hundred and sixty subjects were recruited into the study. Data from 58 adolescent and 14 adult volunteers and from 42 adult patients were used for technical comparisons (n = 114). Body composition information was evaluated (n = 102) for 60 adult volunteers and 42 patients (17 with eating disorders, 7 with chronic alcoholic pancreatitis and 18 with inflammatory bowel disease).
Estimation of bias, limits of agreement and correlations on data from the three machines. Relationships between percentage body mass as lean, absolute weights and body mass index, in the adult subjects.
Both resistance and calculated impedance measured by the hand-held machine significantly correlated with the impedance measured by the in-house machine (r = 0.996; P < 0.0001). An estimation of the level of agreement in percentage lean measurement between dual energy x-ray absorptiometry and hand-held bioelectrical impedance analysis machine by the Bland and Altman method showed a bias of -0.07% and satisfactory limits of agreement from -7.97% to 7.76%. Body mass index was similar in the groups of healthy men and women, but proportion of weight as lean was significantly higher in men than women. In underweight patients with eating disorders, the ratio of lean to fat varied widely; in inflammatory bowel disease patients, proportions of lean and fat were similar to controls; however patients with alcoholic pancreatitis had values for body mass index similar to controls, but had significantly lower proportion of their body weight as lean (P < 0.05).
In non-obese and thin adults, an accurate two-compartment (lean, fat) measurement of body composition can be made in 10 min by using an inexpensive, hand-held, bioelectric impedance analysis machine.
通过与标准仪器和技术（一台内部生物电阻抗分析仪和双能X线吸收法）进行技术比较，并对潜在营养不良患者群体进行身体成分分析，评估一种用于测量瘦体重的廉价手持式生物电阻抗分析仪的使用情况。
对手持式和内部生物电分析仪以及双能X线吸收法所做测量进行前瞻性同步比较。
一所大学教学医院的医学物理科和胃肠科。
研究对象/方法：160名受试者被纳入研究。58名青少年和14名成年志愿者以及42名成年患者的数据用于技术比较（n = 114）。对60名成年志愿者和42名患者（17名饮食失调患者、7名慢性酒精性胰腺炎患者和18名炎症性肠病患者）的身体成分信息进行了评估（n = 102）。
对三台仪器的数据进行偏差估计、一致性界限和相关性分析。成年受试者中瘦体重百分比、绝对体重和体重指数之间的关系。
手持式仪器测量的电阻和计算出的阻抗与内部仪器测量的阻抗显著相关（r = 0.996；P < 0.0001）。采用Bland和Altman方法对双能X线吸收法和手持式生物电阻抗分析仪在瘦体重测量百分比方面的一致性水平进行估计，结果显示偏差为 -0.07%，一致性界限令人满意，为 -7.97%至7.76%。健康男性和女性组的体重指数相似，但男性的瘦体重比例显著高于女性。在体重过轻的饮食失调患者中，瘦体重与脂肪的比例差异很大；在炎症性肠病患者中，瘦体重和脂肪的比例与对照组相似；然而，酒精性胰腺炎患者的体重指数与对照组相似，但其瘦体重占体重的比例显著较低（P < 0.05）。
在非肥胖和消瘦的成年人中，使用一种廉价手持式生物电阻抗分析仪可在10分钟内准确进行两部分（瘦体重、脂肪）身体成分测量。
