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Clozapine withdrawal: serotonergic or dopaminergic mechanisms?

作者信息

Meltzer H Y

出版信息

Arch Gen Psychiatry. 1997 Aug;54(8):760-3. doi: 10.1001/archpsyc.1997.01830200094013.

DOI:10.1001/archpsyc.1997.01830200094013
PMID:9283512
Abstract
摘要

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Unique receptor-blockading profile of clozapine.氯氮平独特的受体阻断特性。
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Emergence of obsessive--compulsive symptoms and tics during clozapine withdrawal.氯氮平撤药期间强迫症状和抽动的出现。
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High-dose Clozapine Withdrawal: A Case Report and Timeline of a Single Potential Withdrawal Seizure.高剂量氯氮平撤药：一例报告及单次潜在撤药癫痫发作的时间线
Innov Clin Neurosci. 2019 Jul 1;16(7-08):22-24. eCollection 2019 Jul-Aug.
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Clozapine response trajectories and predictors of non-response in treatment-resistant schizophrenia: a chart review study.氯氮平治疗反应轨迹和治疗抵抗性精神分裂症无反应的预测因素：一项图表回顾研究。
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Withdrawal symptoms and rebound syndromes associated with switching and discontinuing atypical antipsychotics: theoretical background and practical recommendations.
与切换和中断使用非典型抗精神病药物相关的戒断症状和反弹综合征：理论背景和实际建议。
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Mechanisms of action of antipsychotic drugs of different classes, refractoriness to therapeutic effects of classical neuroleptics, and individual variation in sensitivity to their actions: Part II.不同类别抗精神病药物的作用机制、对经典神经阻滞剂治疗效果的耐药性以及对其作用的个体敏感性的个体差异：第二部分。
Curr Neuropharmacol. 2009 Dec;7(4):315-30. doi: 10.2174/157015909790031184.
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Clozapine versus typical neuroleptic medication for schizophrenia.氯氮平与传统抗精神病药物治疗精神分裂症的比较。
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Effect of anticholinergics in preventing acute deterioration in patients undergoing abrupt clozapine withdrawal.抗胆碱能药物在预防突然停用氯氮平患者急性病情恶化中的作用。
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