Tupker R A, Willis C, Berardesca E, Lee C H, Fartasch M, Agner T, Serup J
Department of Dermatological Research, Leo Pharmaceutical Products, Ballerup, Denmark.
Contact Dermatitis. 1997 Aug;37(2):53-69. doi: 10.1111/j.1600-0536.1997.tb00041.x.
This report reviews the clinical and histopathological reactions caused by sodium lauryl sulfate (SLS), and the non-invasive methods that can characterize these reactions. Furthermore, SLS exposure techniques and factors that may influence the outcome of these exposures are discussed. Finally, guidelines are introduced for each exposure technique in order to have a uniform approach to SLS testing in man. Since different study aims warrant different testing conditions, we have proposed 2 categories, namely susceptibility testing and provocative testing, tailored to the aim with which the study is performed.
本报告回顾了月桂醇硫酸酯钠（SLS）引起的临床和组织病理学反应，以及能够表征这些反应的非侵入性方法。此外，还讨论了SLS暴露技术以及可能影响这些暴露结果的因素。最后，针对每种暴露技术引入了指导方针，以便在人体进行SLS测试时采用统一的方法。由于不同的研究目的需要不同的测试条件，我们提出了两类测试，即敏感性测试和激发性测试，根据研究目的进行量身定制。
