Layfield L J, Glasgow B J, Hirschcowitz S, Dodd L G
Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Diagn Cytopathol. 1997 Sep;17(3):223-9. doi: 10.1002/(sici)1097-0339(199709)17:3<223::aid-dc11>3.0.co;2-h.
The recognition of intramammary lymphoid proliferations is important because smears of these proliferations would be judged as insufficient by several of the published criteria for specimen adequacy. Alternatively, some might be confused with medullary carcinoma of the breast or adenocarcinomas with a "single-cell" pattern. We found 19 intramammary lymphoid proliferations in a series of 887 fine-needle aspirates of palpable breast nodules. Six were lymphomas and 13 were benign intramammary lymph nodes. Smear cellularity ranged from scant to high, but in all cases, lymphocytes dominated the cell population. The cytology of intramammary lymph nodes and lymphoma did not differ from those occurring at other sites.
乳腺内淋巴样增生的识别很重要,因为根据已发表的多项标本充足性标准,这些增生的涂片会被判定为不充分。另外,有些可能会与乳腺髓样癌或具有“单细胞”模式的腺癌相混淆。在一系列887例可触及乳腺结节的细针穿刺抽吸物中,我们发现了19例乳腺内淋巴样增生。其中6例为淋巴瘤,13例为乳腺内良性淋巴结。涂片细胞丰富度从稀少到丰富不等,但在所有病例中,淋巴细胞在细胞群中占主导地位。乳腺内淋巴结和淋巴瘤的细胞学表现与发生在其他部位的并无差异。