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Involvement of transforming growth factor-beta and its receptors in the pathogenesis of diabetic nephrology.

作者信息

Ziyadeh F N, Han D C

机构信息

Penn Center for Molecular Studies of Kidney Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA.

出版信息

Kidney Int Suppl. 1997 Sep;60:S7-11.

PMID:9285895
Abstract
摘要

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Kidney Int Suppl. 1997 Sep;60:S7-11.
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Expression of transforming growth factor-beta1 and transforming growth factor-beta receptors in hepatocellular carcinoma and dysplastic nodules.转化生长因子-β1及转化生长因子-β受体在肝细胞癌和发育异常结节中的表达
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糖尿病肾病的病理生理学。
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Enhanced TGF-beta/Smad signaling in the early stage of diabetic nephropathy is independent of the AT1a receptor.糖尿病肾病早期增强的转化生长因子-β/信号转导和转录激活因子信号不依赖于1a型血管紧张素受体。
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