van Dijken J W, Kalfas S, Litra V, Oliveby A
Department of Oral Biology, Dental School, Umeå University, Umeå, Sweden.
Caries Res. 1997;31(5):379-83. doi: 10.1159/000262422.
The use of fluoride-releasing restoratives such as glass ionomer cements (GICs) has increased during the last decade. The antibacterial effect of released fluoride is thought to be a possible caries-preventive effect of these restorations. In this study fluoride concentrations in plaque on 1-year old resin-modified GIC, compomer and resin composite restorations were compared intraindividually and related to the occurrence of caries-associated bacteria. Plaque from class III restorations of the three restorative materials and from a proximal enamel surface in 18 individuals was analysed. Low fluoride levels were detected in all the samples, while the resin-modified GIC samples showed significantly higher amounts. The distribution of oral streptococci, mutans streptococci and lactobacilli did not differ significantly among the surfaces and did not correlate to the fluoride levels in the samples. A good correlation was found between the counts of mutans streptococci in saliva and their proportions in the plaque. The results indicate that the fluoride concentrations released in vivo from 1-year-old restoratives are not high enough to affect the plaque levels of the caries-associated bacteria mutans streptococci and lactobacilli.
在过去十年中，诸如玻璃离子水门汀（GICs）等释氟修复材料的使用有所增加。释放的氟化物的抗菌作用被认为是这些修复体可能具有的防龋作用。在本研究中，对18名个体的1岁树脂改性GIC、复合体和树脂复合材料修复体上菌斑中的氟化物浓度进行了个体内比较，并与龋相关细菌的发生情况相关联。分析了三种修复材料的III类修复体以及18名个体近中釉质表面的菌斑。在所有样本中均检测到低氟水平，而树脂改性GIC样本显示出明显更高的含量。口腔链球菌、变形链球菌和乳酸菌在不同表面的分布没有显著差异，且与样本中的氟化物水平无关。在唾液中变形链球菌的计数与其在菌斑中的比例之间发现了良好的相关性。结果表明，1岁修复体在体内释放的氟化物浓度不足以影响龋相关细菌变形链球菌和乳酸菌的菌斑水平。
