White R I, Strandberg J V, Gross G S, Barth K H
Radiology. 1977 Dec;125(3):677-87. doi: 10.1148/125.3.677.
The effects of long-term occlusion of branches of the celiac and renal arteries were studied in 13 pigs, using isobutyl 2-cyanoacrylate (ibc), the Gianturco-Anderson-Wallace wool coil, and lvalon. IBC permanently occluded 2- to 8-cm lengths of both vessels, including their branches so that collateral circulation was not able to preserve the tissue supplied by the occluded artery. Gastric ulcers, splenic and hepatic infarcts, and large, sterile biliary cysts were observed on postmortem examination. Permanent occlusion was also observed with the wool coil and lvalon, but the pathological results were much less deleterious. The authors conclude that IBC is presently unsafe for use in branches of the celiac artery.
在13头猪身上研究了长期闭塞腹腔动脉和肾动脉分支的影响，使用了异丁基2-氰基丙烯酸酯（IBC）、吉安图尔科-安德森-华莱士羊毛线圈和Ivalon。IBC永久性闭塞了这两种血管2至8厘米的长度，包括其分支，因此侧支循环无法保护被闭塞动脉所供应的组织。尸检时观察到胃溃疡、脾梗死和肝梗死以及大的无菌性胆管囊肿。使用羊毛线圈和Ivalon也观察到了永久性闭塞，但病理结果的危害性要小得多。作者得出结论，目前IBC用于腹腔动脉分支是不安全的。
