DeNardo G L, DeNardo S J, Barnett C A, Newcomer K A, Jansholt A L, Carretta R F, Rose A W
Radiology. 1977 Dec;125(3):765-8. doi: 10.1148/125.3.765.
Analysis of 55 positive tests of a total of 300 tests by conventional criteria revealed that 125I-fibrinogen provides useful information early enough for clinical management. Of the tests which were ultimately interpreted as positive by conventional criteria, at least one was positive at 3-4 hours in 67% of the tests and 98% of the tests were positive at 24 hours after the administration of 125I-fibrinogen. A 20% difference between contralateral identical locations of the legs and a 20% difference between adjacent locations of the ipsilateral leg were found with almost equal frequency in the positive tests, whereas a 20% increase at the same location was less sensitive. The 125I-fibrogen uptake test is a simple and accurate technique for early diagnosis of active thrombophlebitis.
按照传统标准对总共300次检测中的55次阳性检测进行分析后发现，125I-纤维蛋白原能足够早地提供对临床管理有用的信息。在最终按照传统标准判定为阳性的检测中，67%的检测在3 - 4小时时至少有一次呈阳性，98%的检测在注射125I-纤维蛋白原后24小时呈阳性。在阳性检测中，双腿对侧相同部位20%的差异和同侧腿相邻部位20%的差异出现频率几乎相同，而同一部位20%的增加则不太敏感。125I-纤维蛋白原摄取试验是早期诊断活动性血栓性静脉炎的一种简单而准确的技术。
