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全球结核病控制评估。世界卫生组织全球监测项目

Assessment of worldwide tuberculosis control. WHO Global Surveillance and Monitoring Project.

作者信息

Raviglione M C, Dye C, Schmidt S, Kochi A

机构信息

Global Tuberculosis Programme, World Health Organization, Geneva, Switzerland.

出版信息

Lancet. 1997 Aug 30;350(9078):624-9. doi: 10.1016/s0140-6736(97)04146-9.

Abstract

BACKGROUND

Because worldwide tuberculosis (TB) control had never been assessed, WHO set up a surveillance and monitoring project in 1995. The objectives were to assess the performance of national TB programmes; to assess the extent of implementation of the WHO strategy of TB control; and to attempt a comparison between regions that had adopted the WHO strategy and those that had not.

METHODS

In June, 1996, we sent data-collection forms requesting information on national TB programmes' control policies, 1995 case notifications, and 1994 treatment results to 216 countries, areas, and territories. We assessed the performance of national TB programmes by comparing case notifications with estimated incidence and by outcome of treatment in cohorts of patients. We also investigated worldwide treatment success and case detection among sputum-smear-positive patients.

FINDINGS

180 (83%) of the 216 countries, areas, and territories surveyed replied to WHO (98% of the worldwide population). In 1995, the WHO control strategy had been implemented in 75 countries, and in 39 of these implementation was countrywide. UP to 23% of the worldwide population lived in regions where the strategy was available. In 1995, 3 297 688 cases of TB (all types) were reported, of which 1161411 (35%) were sputum-smear positive. 54% of all reported cases in countries that used the WHO strategy were sputum-smear positive, compared with 30% in other countries. The worldwide case-detection rate of new sputum-smear-positive cases was 35%. 92% of cases registered for treatment in 1994 in regions that used WHO strategy were assessed for outcome and 76% were treated successfully, compared with 54% and 42%, respectively, in regions that had not implemented the WHO strategy. Among cases reported worldwide in 1994, the documented treatment-success rate was 43%.

INTERPRETATION

National TB programmes that have adopted the WHO TB control strategy achieve higher cure rates, but their impact on TB is modest on a worldwide scale. Wider continuous coverage with the WHO strategy is needed for effective worldwide TB control.

摘要

背景

由于此前从未对全球结核病控制情况进行过评估,世界卫生组织于1995年设立了一个监测项目。其目标是评估各国结核病规划的执行情况;评估世界卫生组织结核病控制策略的实施程度;并尝试对采用世界卫生组织策略的地区和未采用该策略的地区进行比较。

方法

1996年6月,我们向216个国家、地区和领地发送了数据收集表,要求提供有关各国结核病规划控制政策、1995年病例通报情况以及1994年治疗结果的信息。我们通过将病例通报数与估计发病率进行比较以及根据患者队列的治疗结果来评估各国结核病规划的执行情况。我们还调查了全球范围内痰涂片阳性患者的治疗成功率和病例发现率。

结果

在接受调查的216个国家、地区和领地中,有180个(83%)回复了世界卫生组织(占全球人口的98%)。1995年,世界卫生组织控制策略已在75个国家实施,其中39个国家在全国范围内实施。全球高达23%的人口生活在可获取该策略的地区。1995年,共报告了3297688例各类结核病病例,其中1161411例(35%)痰涂片呈阳性。在采用世界卫生组织策略的国家,所有报告病例中有54%痰涂片呈阳性,而在其他国家这一比例为30%。全球新痰涂片阳性病例的病例发现率为35%。1994年在采用世界卫生组织策略的地区登记接受治疗的病例中,92%的病例接受了治疗结果评估,76%的病例治疗成功,而在未实施世界卫生组织策略的地区,这两个比例分别为54%和42%。在1994年全球报告的病例中,有记录的治疗成功率为43%。

解读

采用世界卫生组织结核病控制策略的国家结核病规划实现了更高的治愈率,但在全球范围内其对结核病的影响不大。要在全球有效控制结核病,需要更广泛持续地推行世界卫生组织策略。

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