Antidiuretic hormone and psychosomatic aspects in Menière's disease.

We studied the relation between psychosomatic profiles of patients with Menière's disease and antidiuretic hormone (ADH). For investigation of the psychosomatic aspects, we used the Cornell Medical Index (CMI), Yatabe-Guilford personality (Y-G) test and the originally produced stress questionnaire. In Y-G test, patients with Menière's disease are classified in normal group. In the CMI test, on the other hand, types III and IV were significantly more often observed in Menière's disease than normal control (chi 2 test, p < 0.05). However, the CMI test results have no correlation to plasma ADH (p-ADH) levels. The survey of our original questionnaire revealed that stress has a close relationship to vertiginous attacks. Further, high p-ADH levels were significantly frequently observed in cases with stress compared with cases without stress (t-test, p < 0.05).