Silvoniemi P, Suonpää J, Sipilä J, Grénman R, Erkinjuntti M
Department of Otorhinolaryngology, Turku University Central Hospital, Finland.
Acta Otolaryngol Suppl. 1997;529:199-201. doi: 10.3109/00016489709124121.
The role of nasal obstruction in etiology of the sleep apnea disease is controversial in literature. Forty-six subjects (3 women, 43 men) with severe nasal obstruction due to septal deviation were evaluated. The examination included case history, clinical ORL examination by ENT specialist, rhinomanometry and whole night sleep recording (SCSB, oximetry, EKG). Mean age of the patients was 40.0 years (from 17 to 68 years) and body mass index 26.0 kg/m2 (from 20.3 to 34.6 kg/m2). The chief complaint of the patients was a severe nasal obstruction. Thirty-one patients (67%) had also heavy disturbing snoring, and apnea periods during sleep were reported by 10 cases. The evaluation of the sleep recordings revealed 12 cases with partial upper airway obstruction (26%), 1 case with severe airway obstruction, 1 case with mixed type of obstructive apnea and 3 cases with periodic limb movements. Evaluation of the oxygen desaturation of the blood revealed only 6 cases with significant disturbance (pO2 below 90% level). As a final result we conclude that severe nasal obstruction can lead to breathing disturbance during sleep.
鼻阻塞在睡眠呼吸暂停疾病病因学中的作用在文献中存在争议。对46例因鼻中隔偏曲导致严重鼻阻塞的受试者（3名女性，43名男性）进行了评估。检查包括病史、耳鼻喉科专家进行的临床耳鼻喉检查、鼻阻力测量和整夜睡眠记录（同步多导睡眠图、血氧饱和度测定、心电图）。患者的平均年龄为40.0岁（17至68岁），体重指数为26.0kg/m²（20.3至34.6kg/m²）。患者的主要诉求是严重的鼻阻塞。31例患者（67%）还伴有严重的令人困扰的打鼾，10例报告有睡眠期间的呼吸暂停期。睡眠记录评估显示12例有部分上气道阻塞（26%），1例有严重气道阻塞，1例有混合型阻塞性呼吸暂停，3例有周期性肢体运动。血液氧饱和度评估显示只有6例有明显异常（动脉血氧分压低于90%水平）。最终我们得出结论，严重鼻阻塞可导致睡眠期间的呼吸紊乱。
