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鼻腔呼吸障碍对睡眠呼吸紊乱的影响。

Impact of impaired nasal breathing on sleep-disordered breathing.

作者信息

Verse Thomas, Pirsig Wolfgang

机构信息

University ENT Clinic Mannheim, Mannheim, Germany.

出版信息

Sleep Breath. 2003 Jun;7(2):63-76. doi: 10.1007/s11325-003-0063-2.

Abstract

OBJECTIVE

The role of the nose and its importance in the development and severity of sleep-disordered breathing (SDB) is still a matter of discussion. In the first part of this study, often-controversial data and theories about the nose are reviewed concerning its influence on the pathophysiology of SDB and to interpret certain clinical findings connected with impaired nasal breathing. In the second part, the effectiveness of some nonsurgical and surgical therapies is evaluated.

METHOD

A worldwide literature research (Medline) was the basis for this review.

RESULTS

The study of the literature on nasal resistance and clinical findings about the effects of incomplete or complete nasal blockage, particularly in comparison of healthy persons and persons with SDB, allows the assumption of the existence of two different groups of responders: a larger group where the importance of the nose for SDB is negligible and a smaller group where the influence of the nose on SDB is crucial. The same seems to hold true for the responses to nonsurgical and surgical treatments with only a few surgical results available in the literature. While the success rate of nasal surgery for patients with obstructive sleep apnea, for instance, seems to be less than 20%, the normalization of nasal resistance often leads to a positive impact on the well-being and the sleep quality of these patients. However, because criteria to identify responders are lacking, the prediction of success of any treatment for the individual with SDB is not possible.

摘要

目的

鼻子在睡眠呼吸障碍(SDB)的发生发展及严重程度中的作用仍存在争议。在本研究的第一部分,我们回顾了关于鼻子的一些常引发争议的数据和理论,涉及鼻子对SDB病理生理学的影响,并对与鼻呼吸受损相关的某些临床发现进行解读。在第二部分,我们评估了一些非手术和手术治疗方法的有效性。

方法

本综述以全球范围的文献研究(Medline)为基础。

结果

对有关鼻阻力的文献以及关于不完全或完全鼻阻塞影响的临床发现进行研究,尤其是在健康人与SDB患者之间进行比较后,我们可以假定存在两组不同的反应者:一组人数较多,鼻子对SDB的重要性可忽略不计;另一组人数较少,鼻子对SDB的影响至关重要。对于非手术和手术治疗的反应似乎也是如此,不过文献中仅有少量手术结果。例如,对于阻塞性睡眠呼吸暂停患者,鼻手术的成功率似乎不到20%,但鼻阻力的正常化通常会对这些患者的健康状况和睡眠质量产生积极影响。然而,由于缺乏识别反应者的标准,无法预测SDB个体接受任何治疗的成功率。

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