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NMR and stable isotope techniques for studies of liver metabolism in man.

作者信息

Roden M

机构信息

Department of Internal Medicine III. University of Vienna, Austria.

出版信息

Horm Metab Res. 1997 Jul;29(7):340-3. doi: 10.1055/s-2007-979049.

DOI:10.1055/s-2007-979049
PMID:9288565
Abstract

The pivotal role of the liver for glucose homeostasis resides within its ability to store large amounts of glucose in the form of glycogen, but also to rapidly release glucose into the circulation (1,2). Despite extensive studies on liver glycogen metabolism in vitro, studies in humans were limited to measurements of glycogen content by biopsy (3) before the introduction of in vivo 13C NMR spectroscopy for monitoring of hepatic glycogen in man (4).

摘要

相似文献

1
NMR and stable isotope techniques for studies of liver metabolism in man.
Horm Metab Res. 1997 Jul;29(7):340-3. doi: 10.1055/s-2007-979049.
2
Dynamic human glycogen and glucose metabolism detection utilizing in vivo 13C NMR.利用体内¹³C核磁共振技术进行动态人体糖原和葡萄糖代谢检测。
Am J Physiol Imaging. 1992 Jan-Mar;7(1):32-5.
3
Observation of glucose metabolism in the rat liver by in vivo 13C MR spectroscopy without proton decoupling.在不进行质子去耦的情况下,通过体内¹³C磁共振波谱法观察大鼠肝脏中的葡萄糖代谢。
Radiat Med. 1995 Jul-Aug;13(4):195-7.
4
Glucose and energy metabolism in rat liver after ischemic damage assessed by 13 C and 31 P NMR spectroscopy.通过¹³C和³¹P核磁共振波谱法评估大鼠肝脏缺血损伤后的葡萄糖和能量代谢。
J Surg Res. 1996 Jul 1;63(2):393-9. doi: 10.1006/jsre.1996.0282.
5
Contribution of net hepatic glycogen synthesis to disposal of an oral glucose load in humans.肝脏净糖原合成对人体口服葡萄糖负荷处置的贡献。
Metabolism. 2001 May;50(5):598-601. doi: 10.1053/meta.2001.22561.
6
[Importance of the liver in diabetes mellitus].[肝脏在糖尿病中的重要性]
Med Klin. 1980 Nov 21;75(24):844-7.
7
Metabolic investigations in humans by in vivo nuclear magnetic resonance. Recommendations of ALFEDIAM (French Language Association for the Study of Diabetes and Metabolic Diseases).通过体内核磁共振对人体进行的代谢研究。ALFEDIAM(法语糖尿病和代谢疾病研究协会)的建议。
Diabetes Metab. 1997 Sep;23(4):343-50.
8
Normal hepatic glycogen storage after fasting and feeding in children and adolescents with type 1 diabetes.1型糖尿病儿童及青少年禁食和进食后的正常肝糖原储存情况。
Pediatr Diabetes. 2003 Jun;4(2):70-6. doi: 10.1034/j.1399-5448.2003.00015.x.
9
Stable isotope techniques for the study of gluconeogenesis in man.用于研究人体糖异生作用的稳定同位素技术。
Horm Metab Res. 1997 Jul;29(7):334-6. doi: 10.1055/s-2007-979047.
10
Sources of plasma glucose and liver glycogen in fasted ob/ob mice.禁食的ob/ob小鼠血浆葡萄糖和肝糖原的来源
Acta Diabetol. 2005 Dec;42(4):187-93. doi: 10.1007/s00592-005-0201-3.

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1
Changes in hepatic glycogen cycling during a glucose load in healthy humans.健康人葡萄糖负荷期间肝脏糖原循环的变化。
Diabetologia. 2006 Feb;49(2):360-8. doi: 10.1007/s00125-005-0099-x. Epub 2005 Dec 28.