Taşkan I, Ozyazgan I, Tercan M, Kardaş H Y, Balkanli S, Saraymen R, Zorlu U, Ozügül Y
Physical Therapy and Rehabilitation Center, Medical Faculty of Inönü University, Istanbul, Turkey.
Plast Reconstr Surg. 1997 Sep;100(4):966-72. doi: 10.1097/00006534-199709001-00020.
A comparative study has been carried out to investigate the effects of electrical stimulation and ultrasound on wound healing. Eighty-four female rats were divided into four groups depending on the treatment received. The first group was given electrical stimulation of 300 microA direct current, 30 minutes daily, starting with negative polarity and then changed after 3 days of treatment. Group 2 received sham electrostimulation treatment. The third group received 0.1 W/cm2 pulsed ultrasound using the moving applicator technique for 5 minutes a day. Group 4 received sham ultrasound treatment. A total of 7 days of treatment was given to all groups. Histopathologic and biochemical analyses on the fourth and seventh days and wound breaking strength on the twenty-fifth day were performed for all groups. By accelerating the inflammatory phase, electrical stimulation had progressed the proliferative phase of wound healing earlier than ultrasound had done. Both electrical stimulation and ultrasound have positive effects on proliferative phases, but electrical stimulation was superior to ultrasound at the maturation phase. There was no difference between the two experimental groups on the mast cell reduction effect. Although ultrasound treatment may seem to be efficient in terms of time, when the effects of electrical stimulation and ultrasound on wound healing with the methods employed in our study are considered, it is concluded that electrical stimulation is a means of treatment superior to ultrasound in wound healing.
一项比较研究已开展，以调查电刺激和超声对伤口愈合的影响。84只雌性大鼠根据接受的治疗被分为四组。第一组给予300微安直流电刺激，每天30分钟，开始为负极性，治疗3天后更换。第二组接受假电刺激治疗。第三组使用移动探头技术每天接受0.1瓦/平方厘米的脉冲超声治疗5分钟。第四组接受假超声治疗。所有组均给予7天的治疗。对所有组在第4天和第7天进行组织病理学和生化分析，并在第25天进行伤口抗张强度检测。通过加速炎症期，电刺激比超声更早地推进了伤口愈合的增殖期。电刺激和超声对增殖期均有积极作用，但在成熟阶段电刺激优于超声。两个实验组在肥大细胞减少效果上没有差异。尽管超声治疗在时间方面似乎有效，但考虑到电刺激和超声在本研究采用的方法对伤口愈合的影响，得出的结论是电刺激是伤口愈合中优于超声的一种治疗手段。
