肾移植受者脑脓肿：三例报告
Brain abscess in renal transplant recipients: report of three cases.
作者信息
Gupta S K, Manjunath-Prasad K S, Sharma B S, Khosla V K, Kak V K, Minz M, Sakhuja V K
机构信息
Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
出版信息
Surg Neurol. 1997 Sep;48(3):284-7. doi: 10.1016/s0090-3019(97)80036-5.
BACKGROUND
Neurologic complications occur in about 30% of renal transplant patients, infections being the most common. We encountered three such patients and present our experience in the management of such cases.
CLINICAL MATERIAL
Three cases of brain abscess in renal transplant recipients are reported. These patients presented from 9-60 months after the transplant. One patient had a pyogenic abscess; in the second the organism identified was Nocardia asteroides; in the third, a fungal infection was responsible. In two patients excision of the abscess was done, while in one repeated aspirations with intracavitary antibiotics were used. All received systemic antimicrobial therapy.
CONCLUSIONS
Central nervous system (CNS) complications, specifically infections, are quite common in renal transplant recipients, but reports of brain abscesses in these patients are very rare. The treatment options for such patients are discussed.
背景
约30%的肾移植患者会出现神经系统并发症，其中感染最为常见。我们遇到了3例这样的患者，并介绍我们对此类病例的处理经验。
临床资料
报告了3例肾移植受者脑脓肿病例。这些患者在移植后9至60个月发病。1例为化脓性脓肿；第2例鉴定出的病原体为星形诺卡菌；第3例为真菌感染。2例行脓肿切除术，1例采用反复穿刺并腔内注入抗生素治疗。所有患者均接受了全身抗菌治疗。
结论
中枢神经系统（CNS）并发症，尤其是感染，在肾移植受者中相当常见，但这些患者发生脑脓肿的报道非常罕见。本文讨论了此类患者的治疗选择。
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