Reis Miranda D, Moreno R, Iapichino G
Department of Surgery, University Hospital Groningen, The Netherlands.
Intensive Care Med. 1997 Jul;23(7):760-5. doi: 10.1007/s001340050406.
To develop a simplified Therapeutic Intervention Scoring System (TISS) based on the TISS-28 items and to validate the new score in an independent database.
Retrospective statistical analysis of a database and a prospective multicentre study.
Development in the database of the Foundation for Research on Intensive Care in Europe with external validation in 64 intensive care units (ICUs) of 11 European countries.
Development of NEMS on a random sample of TISS-28 items, cross validation on another random sample of TISS-28, and external validation of NEMS in comparison with TISS-28 scored by two independent raters on the day of the visit to the ICUs participating in an international study. Multivariable regression techniques, Pearson's correlation, and paired sample t-tests were used (significance at p < 0.05 level). Intraclass correlation, rate of agreement, and kappa statistics were used for interrater reliability tests. The TISS-28 items were reduced to NEMS (9 items) in a random sample of 2000 records; the means of the two scores were no different: TISS-28 26.23 +/- 10.38, NEMS 26.19 +/- 9.12, NS. Cross-validation in a random sample of 996 records; mean TISS-28 26.13 +/- 10.38, NEMS 26.17 +/- 9.38, NS; R2 = 0.76. External validation on 369 pairs of TISS-28 and NEMS has shown that the means of the two scores were no different: TISS-28 27.56 +/- 11.03, NEMS 27.02 +/- 8.98, NS; R2 = 0.59. Reliability tests have shown an "almost perfect" interrater correlation. Similar to studies correlating TISS with Simplified Acute Physiology Score (SAPS)-I and/or Acute Physiology and Chronic Health Evaluation II scores, the value of NEMS scored on the first day accounts for 30.4% of the variation of SAPS-II score.
NEMS is a suitable therapeutic index to measure nursing workload at the ICU level. The use of NEMS is indicated for: (a) multicentre ICU studies; (b) management purposes in the general (macro) evaluation and comparison of workload at the ICU level; (c) the prediction of workload and planning of nursing staff allocation at the individual patient level.
基于TISS - 28项条目开发一个简化的治疗干预评分系统(TISS),并在一个独立数据库中验证新评分。
对一个数据库进行回顾性统计分析以及一项前瞻性多中心研究。
在欧洲重症监护研究基金会的数据库中开发,在11个欧洲国家的64个重症监护病房(ICU)进行外部验证。
在TISS - 28项条目的随机样本上开发NEMS,在TISS - 28的另一个随机样本上进行交叉验证,并在参与一项国际研究的ICU访视当天,将NEMS与由两名独立评估者评分的TISS - 28进行比较以进行外部验证。使用多变量回归技术、Pearson相关性和配对样本t检验(p < 0.05水平具有显著性)。组内相关性、一致性率和kappa统计量用于评估评估者间的可靠性测试。在2000条记录的随机样本中,TISS - 28项条目被简化为NEMS(9项);两个评分的均值无差异:TISS - 28为26.23±10.38,NEMS为26.19±9.12,无显著性差异。在996条记录的随机样本中进行交叉验证;TISS - 28均值为26.13±10.38,NEMS均值为26.17±9.38,无显著性差异;R2 = 0.76。对369对TISS - 28和NEMS进行外部验证表明,两个评分的均值无差异:TISS - 28为27.56±11.03,NEMS为27.02±8.98,无显著性差异;R2 = 0.59。可靠性测试显示评估者间具有“近乎完美”的相关性。与将TISS与简化急性生理学评分(SAPS)-I和/或急性生理学与慢性健康评估II评分相关联的研究类似,第一天的NEMS评分值占SAPS - II评分变异的30.4%。
NEMS是衡量ICU护理工作量的合适治疗指标。NEMS的使用适用于:(a)多中心ICU研究;(b)在对ICU护理工作量进行总体(宏观)评估和比较时用于管理目的;(c)在个体患者层面预测护理工作量和规划护理人员分配。