Mathur A, Wallenius K, Abdulla M
Scand J Clin Lab Invest. 1977 Sep;37(5):469-72.
Measurements were made of zinc levels in saliva, whole blood and plasma as well as copper levels in plasma by atomic absorption spectrophotometry. The mean zinc concentration (in ppm) was 0.478 (n = 136) in resting mixed saliva, 0.046 (n = 36) in parotid saliva, 6.41 (n = 145) in whole blood and 0.87 (n = 145) in plasma. The whole blood zinc levels were significantly lower in females than in males (P less than 0.001). Females and blood donors (males) had a significantly (P less than 0.001) higher Cu:Zn ratio than males (non-donors). It would thus appear, first, that the local effect of salivary zinc cannot be assessed simply from the concentration of zinc in stimulated parotid saliva since about nine-tenths of the zinc in resting mixed saliva is derived from other sources and, second, that the Cu:Zn in plasma is the most eligible variable for detecting sub-clinical Zn deficiency.
通过原子吸收分光光度法对唾液、全血和血浆中的锌水平以及血浆中的铜水平进行了测量。静息混合唾液中的平均锌浓度（以ppm计）为0.478（n = 136），腮腺唾液中为0.046（n = 36），全血中为6.41（n = 145），血浆中为0.87（n = 145）。女性全血锌水平显著低于男性（P < 0.001）。女性和献血者（男性）的铜锌比显著高于男性（非献血者）（P < 0.001）。因此，首先似乎可以看出，不能仅根据刺激腮腺唾液中的锌浓度来评估唾液锌的局部作用，因为静息混合唾液中约十分之九的锌来自其他来源；其次，血浆中的铜锌比是检测亚临床锌缺乏最适宜的变量。
