Wahlgren D R, Hovell M F, Slymen D J, Conway T L, Hofstetter C R, Jones J A
Center for Behavioral Epidemiology and Community Health, Graduate School of Public Health, San Diego State University, California 92182, USA.
Tob Control. 1997 Summer;6(2):95-103. doi: 10.1136/tc.6.2.95.
To test whether baseline data from a randomised clinical trial are predictive of initiation of tobacco use over a two-year follow-up interval, and to discuss results in the context of a theoretical model.
Secondary, non-experimental analyses of data collected from a prospective cluster-randomised clinical trial comparing an intervention with a control condition for reduction of tobacco incidence rates. Orthodontic offices in southern California were recruited and randomised to an experimental or control group. Patient participants were sampled within each office, and completed a short survey, repeated two years later.
13,923 patients, 11-18 years of age, randomly sampled from each office.
The ability of baseline data to predict initiation of tobacco use over the two-year follow-up interval was tested through a series of logistic regression models. Significant predictors and their interactions were identified in fixed-effects models, and verified in a mixed-effects logistic regression model to account for cluster randomisation.
Clinician advice against tobacco use was associated with a lower rate of tobacco use initiation among young people whose peer group considered smoking socially desirable. Rates of initiation increased with age, but this association differed by gender and by whether the adolescent had been offered tobacco within 30 days prior to the baseline assessment. People from minority groups were less likely to initiate tobacco use than whites, and young people engaging in other risk practices were more likely to initiate tobacco use.
Findings support predictions based on learning theory that social processes are critical in the development of health-risk behaviours. Future preventive efforts should target changing the density with which young people encounter pro- and anti-tobacco prompts and consequences in the community.
检验一项随机临床试验的基线数据是否能预测两年随访期内烟草使用的开始情况,并在理论模型的背景下讨论结果。
对一项前瞻性整群随机临床试验收集的数据进行二次非实验性分析,该试验比较了一种干预措施与一种对照条件对降低烟草发病率的效果。招募了南加州的正畸诊所并将其随机分为实验组或对照组。在每个诊所内对患者参与者进行抽样,并完成一份简短的调查问卷,两年后重复进行。
从每个诊所随机抽取的13923名11至18岁的患者。
通过一系列逻辑回归模型检验基线数据预测两年随访期内烟草使用开始情况的能力。在固定效应模型中确定显著的预测因素及其相互作用,并在混合效应逻辑回归模型中进行验证,以考虑整群随机化。
临床医生对烟草使用的建议与同龄人认为吸烟在社交上是可取的年轻人中较低的烟草使用开始率相关。开始率随年龄增加,但这种关联因性别以及青少年在基线评估前30天内是否被提供过烟草而有所不同。少数群体的人比白人更不容易开始使用烟草,而从事其他风险行为的年轻人更有可能开始使用烟草。
研究结果支持基于学习理论的预测,即社会过程在健康风险行为的发展中至关重要。未来的预防措施应旨在改变年轻人在社区中接触支持和反对烟草的提示及后果的密度。