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以学校为基础的预防吸烟计划。

School-based programmes for preventing smoking.

作者信息

Thomas Roger E, McLellan Julie, Perera Rafael

机构信息

Department of Family Medicine, Faculty of Medicine, University of Calgary, Calgary, Canada.

出版信息

Cochrane Database Syst Rev. 2013 Apr 30;2013(4):CD001293. doi: 10.1002/14651858.CD001293.pub3.

DOI:10.1002/14651858.CD001293.pub3
PMID:23633306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7028068/
Abstract

BACKGROUND

Helping young people to avoid starting smoking is a widely endorsed public health goal, and schools provide a route to communicate with nearly all young people. School-based interventions have been delivered for close to 40 years.

OBJECTIVES

The primary aim of this review was to determine whether school smoking interventions prevent youth from starting smoking. Our secondary objective was to determine which interventions were most effective. This included evaluating the effects of theoretical approaches; additional booster sessions; programme deliverers; gender effects; and multifocal interventions versus those focused solely on smoking.

SEARCH METHODS

We searched the Cochrane Central Register of Controlled Trials (CENTRAL), the Cochrane Tobacco Addiction Group's Specialised Register, MEDLINE, EMBASE, PsycINFO, ERIC, CINAHL, Health Star, and Dissertation Abstracts for terms relating to school-based smoking cessation programmes. In addition, we screened the bibliographies of articles and ran individual MEDLINE searches for 133 authors who had undertaken randomised controlled trials in this area. The most recent searches were conducted in October 2012.

SELECTION CRITERIA

We selected randomised controlled trials (RCTs) where students, classes, schools, or school districts were randomised to intervention arm(s) versus a control group, and followed for at least six months. Participants had to be youth (aged 5 to 18). Interventions could be any curricula used in a school setting to deter tobacco use, and outcome measures could be never smoking, frequency of smoking, number of cigarettes smoked, or smoking indices.

DATA COLLECTION AND ANALYSIS

Two reviewers independently assessed studies for inclusion, extracted data and assessed risk of bias. Based on the type of outcome, we placed studies into three groups for analysis: Pure Prevention cohorts (Group 1), Change in Smoking Behaviour over time (Group 2) and Point Prevalence of Smoking (Group 3).

MAIN RESULTS

One hundred and thirty-four studies involving 428,293 participants met the inclusion criteria. Some studies provided data for more than one group.Pure Prevention cohorts (Group 1) included 49 studies (N = 142,447). Pooled results at follow-up at one year or less found no overall effect of intervention curricula versus control (odds ratio (OR) 0.94, 95% confidence interval (CI) 0.85 to 1.05). In a subgroup analysis, the combined social competence and social influences curricula (six RCTs) showed a statistically significant effect in preventing the onset of smoking (OR 0.49, 95% CI 0.28 to 0.87; seven arms); whereas significant effects were not detected in programmes involving information only (OR 0.12, 95% CI 0.00 to 14.87; one study), social influences only (OR 1.00, 95% CI 0.88 to 1.13; 25 studies), or multimodal interventions (OR 0.89, 95% CI 0.73 to 1.08; five studies). In contrast, pooled results at longest follow-up showed an overall significant effect favouring the intervention (OR 0.88, 95% CI 0.82 to 0.96). Subgroup analyses detected significant effects in programmes with social competence curricula (OR 0.52, 95% CI 0.30 to 0.88), and the combined social competence and social influences curricula (OR 0.50, 95% CI 0.28 to 0.87), but not in those programmes with information only, social influence only, and multimodal programmes.Change in Smoking Behaviour over time (Group 2) included 15 studies (N = 45,555). At one year or less there was a small but statistically significant effect favouring controls (standardised mean difference (SMD) 0.04, 95% CI 0.02 to 0.06). For follow-up longer than one year there was a statistically nonsignificant effect (SMD 0.02, 95% CI -0.00 to 0.02).Twenty-five studies reported data on the Point Prevalence of Smoking (Group 3), though heterogeneity in this group was too high for data to be pooled.We were unable to analyse data for 49 studies (N = 152,544).Subgroup analyses (Pure Prevention cohorts only) demonstrated that at longest follow-up for all curricula combined, there was a significant effect favouring adult presenters (OR 0.88, 95% CI 0.81 to 0.96). There were no differences between tobacco-only and multifocal interventions. For curricula with booster sessions there was a significant effect only for combined social competence and social influences interventions with follow-up of one year or less (OR 0.50, 95% CI 0.26 to 0.96) and at longest follow-up (OR 0.51, 95% CI 0.27 to 0.96). Limited data on gender differences suggested no overall effect, although one study found an effect of multimodal intervention at one year for male students. Sensitivity analyses for Pure Prevention cohorts and Change in Smoking Behaviour over time outcomes suggested that neither selection nor attrition bias affected the results.

AUTHORS' CONCLUSIONS: Pure Prevention cohorts showed a significant effect at longest follow-up, with an average 12% reduction in starting smoking compared to the control groups. However, no overall effect was detected at one year or less. The combined social competence and social influences interventions showed a significant effect at one year and at longest follow-up. Studies that deployed a social influences programme showed no overall effect at any time point; multimodal interventions and those with an information-only approach were similarly ineffective.Studies reporting Change in Smoking Behaviour over time did not show an overall effect, but at an intervention level there were positive findings for social competence and combined social competence and social influences interventions.

摘要

背景

帮助年轻人避免开始吸烟是一项得到广泛认可的公共卫生目标,学校提供了一条与几乎所有年轻人进行沟通的途径。基于学校的干预措施已经实施了近40年。

目的

本综述的主要目的是确定学校吸烟干预措施是否能防止青少年开始吸烟。我们的次要目的是确定哪些干预措施最有效。这包括评估理论方法的效果;额外的强化课程;项目实施者;性别影响;以及多焦点干预与仅专注于吸烟的干预措施相比的效果。

检索方法

我们检索了Cochrane对照试验中心注册库(CENTRAL)、Cochrane烟草成瘾小组的专业注册库、MEDLINE、EMBASE、PsycINFO、ERIC、CINAHL、Health Star和学位论文摘要,以查找与基于学校的戒烟项目相关的术语。此外,我们筛选了文章的参考文献,并对133位在该领域进行随机对照试验的作者进行了单独的MEDLINE检索。最近一次检索于2012年10月进行。

选择标准

我们选择了随机对照试验(RCT),其中学生、班级、学校或学区被随机分配到干预组与对照组,并随访至少六个月。参与者必须是青少年(5至18岁)。干预措施可以是学校环境中用于阻止烟草使用的任何课程,结果测量指标可以是从不吸烟、吸烟频率、吸烟数量或吸烟指数。

数据收集与分析

两位评审员独立评估研究是否纳入,提取数据并评估偏倚风险。根据结果类型,我们将研究分为三组进行分析:纯预防队列(第1组)、随时间变化的吸烟行为(第2组)和吸烟点患病率(第3组)。

主要结果

134项涉及428,293名参与者的研究符合纳入标准。一些研究为多个组提供了数据。纯预防队列(第1组)包括49项研究(N = 142,447)。在一年或更短时间的随访中,汇总结果发现干预课程与对照组相比没有总体效果(优势比(OR)0.94,95%置信区间(CI)0.85至1.05)。在亚组分析中,综合社会能力和社会影响课程(六项RCT)在预防吸烟开始方面显示出统计学上的显著效果(OR 0.49,95% CI 0.28至0.87;七个分支);而在仅涉及信息的项目(OR 0.12,95% CI 0.00至14.87;一项研究)、仅涉及社会影响的项目(OR 1.00,95% CI 0.88至1.13;25项研究)或多模式干预项目(OR 0.89,95% CI 0.73至1.08;五项研究)中未检测到显著效果。相比之下,最长随访时的汇总结果显示总体上有利于干预的显著效果(OR 0.88,95% CI 0.82至0.96)。亚组分析在具有社会能力课程的项目(OR 0.52,95% CI 0.30至0.88)以及综合社会能力和社会影响课程的项目(OR 0.50,95% CI 0.28至0.87)中检测到显著效果,但在仅涉及信息、仅涉及社会影响和多模式项目中未检测到。随时间变化的吸烟行为(第2组)包括15项研究(N = 45,555)。在一年或更短时间内,有一个小但统计学上显著的有利于对照组的效果(标准化平均差(SMD)0.04,95% CI 0.02至0.06)。对于超过一年的随访,有一个统计学上不显著的效果(SMD 0.02,95% CI -0.00至0.02)。25项研究报告了吸烟点患病率的数据(第3组),尽管该组的异质性过高,无法汇总数据。我们无法分析49项研究(N = 152,544)的数据。亚组分析(仅纯预防队列)表明,在所有课程综合的最长随访中,有利于成年授课者的显著效果(OR 0.88,95% CI 0.81至0.96)。仅针对烟草的干预和多焦点干预之间没有差异。对于有强化课程的课程,仅在综合社会能力和社会影响干预且随访一年或更短时间(OR 0.50,95% CI 0.26至0.96)以及最长随访时(OR 0.51,95% CI 0.27至0.96)有显著效果。关于性别差异的有限数据表明没有总体效果,尽管一项研究发现多模式干预在一年时对男学生有效果。对纯预防队列和随时间变化的吸烟行为结果的敏感性分析表明,选择偏倚和失访偏倚均未影响结果。

作者结论

纯预防队列在最长随访时显示出显著效果,与对照组相比,开始吸烟率平均降低了12%。然而,在一年或更短时间内未检测到总体效果。综合社会能力和社会影响干预在一年和最长随访时显示出显著效果。采用社会影响项目的研究在任何时间点均未显示出总体效果;多模式干预和仅采用信息方法的干预同样无效。报告随时间变化的吸烟行为的研究未显示出总体效果,但在干预层面,社会能力以及综合社会能力和社会影响干预有积极结果。

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