Kemp S F, Lockey R F, Fernández-Caldas E, Arlian L G
Department of Internal Medicine, University of South Florida College of Medicine and the James A. Haley Veterans' Hospital, Tampa, USA.
Clin Exp Allergy. 1997 Aug;27(8):893-7.
The prevalence of sensitization to Euroglyphus maynei (E. maynei) in the United States has not been reported previously.
To determine: (1) the prevalence of skin-test reactivity in allergic subjects to E. maynei compared to D. pteronyssinus, D. farinae, and B. tropicalis and (2) the allergenic crossreactivity between D. pteronyssinus and E. maynei.
Skin testing with extracts of B. tropicalis and E. maynei (1:50 w/v) and standardized D. pteronyssinus and D. farinae extracts (1:50 w/v; 10,000 AU/mL) provided data on 250 subjects (87 males and 163 females) aged 9-77 years (mean age, 39.8 years) with possible allergic respiratory diseases. RAST inhibition assays were used to study crossreactivity between D. pteronyssinus and E. maynei.
One hundred (40%) of 250 subjects had insignificant or no allergic diseases. Of the 150 allergic subjects (53 males, 97 females), 101 (67.3%) had a positive test (a percutaneous test with a weal diameter > or = 3 mm larger than the saline control) to at least one mite species; 60.7%, 60.0%, 28.7%, and 52.0% reacted to D. farinae, D. pteronyssinus, B. tropicalis, and E. maynei, respectively; 40 (26.7%) reacted to the four mite species. Positive tests to D. farinae, D. pteronyssinus, B. tropicalis, or E. maynei alone occurred in six (4.0%), four (2.7%), two (1.3%), and 0%, respectively. D. pteronyssinus and E. maynei showed moderately high crossreactivity in RAST inhibition assays.
There is a high rate of skin-test reactivity to E. maynei in Florida. Moderately high crossreactivity exists between E. maynei and D. pteronyssinus.
此前美国尚未报道过对梅氏嗜霉螨（E. maynei）致敏的患病率。
确定：（1）与粉尘螨、屋尘螨和热带无爪螨相比，过敏受试者对梅氏嗜霉螨皮肤试验反应性的患病率；（2）粉尘螨和梅氏嗜霉螨之间的变应原交叉反应性。
用热带无爪螨和梅氏嗜霉螨提取物（1:50 w/v）以及标准化的粉尘螨和屋尘螨提取物（1:50 w/v；10,000 AU/mL）对250名年龄在9至77岁（平均年龄39.8岁）、可能患有过敏性呼吸道疾病的受试者（87名男性和163名女性）进行皮肤试验，以获取数据。采用放射变应原吸附抑制试验研究粉尘螨和梅氏嗜霉螨之间的交叉反应性。
250名受试者中有100名（40%）无明显过敏疾病或无过敏疾病。在150名过敏受试者（53名男性，97名女性）中，101名（67.3%）对至少一种螨类的皮试呈阳性（皮内试验风团直径比生理盐水对照大≥3 mm）；对粉尘螨、屋尘螨、热带无爪螨和梅氏嗜霉螨有反应的分别占60.7%、60.0%、28.7%和52.0%；40名（26.7%）对这四种螨类均有反应。单独对粉尘螨、屋尘螨、热带无爪螨或梅氏嗜霉螨皮试呈阳性的分别有6名（4.0%）、4名（2.7%）、2名（1.3%）和0%。在放射变应原吸附抑制试验中，粉尘螨和梅氏嗜霉螨显示出中等程度的高交叉反应性。
在佛罗里达州，对梅氏嗜霉螨皮肤试验反应性的发生率很高。梅氏嗜霉螨和粉尘螨之间存在中等程度的高交叉反应性。
