Chertow G M, Rennke H G, Curhan G C, Brady H R
Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Am J Kidney Dis. 1997 Sep;30(3):428-32. doi: 10.1016/s0272-6386(97)90289-4.
The associations among human immunodeficiency virus (HIV) infection, focal segmental glomerulosclerosis, and its variant, "collapsing glomerulopathy," often leading to chronic renal failure, are well described. HIV-seropositive patients may also develop a variety of immune complex-mediated glomerular diseases, including postinfectious glomerulonephritis, IgA nephropathy, and membranoproliferative glomerulonephritis. Herein we describe a case of pauci-immune necrotizing renal vasculitis in an HIV-seropositive patient, thereby expanding the differential diagnosis of acute renal failure in this setting.
人类免疫缺陷病毒（HIV）感染、局灶节段性肾小球硬化及其变体“塌陷性肾小球病”之间的关联已得到充分描述，这些病症常导致慢性肾衰竭。HIV血清阳性患者还可能发生多种免疫复合物介导的肾小球疾病，包括感染后肾小球肾炎、IgA肾病和膜增生性肾小球肾炎。在此，我们描述了一例HIV血清阳性患者发生的少免疫性坏死性肾血管炎病例，从而扩大了这种情况下急性肾衰竭的鉴别诊断范围。
